Literature DB >> 2714436

Recombinant H-chain ferritins: effects of changes in the 3-fold channels.

A Treffry1, P M Harrison, A Luzzago, G Cesareni.   

Abstract

Human H-chain ferritins bearing sequence changes in the 3-fold channels have been expressed in E. coli to investigate the role of these channels in iron-storage processes. The proteins assemble into shells resembling those of native ferritins. Iron uptake measurements indicate that residues in the 3-fold channels are involved neither in initial Fe(II)-oxidation nor in iron-core nucleation.

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Year:  1989        PMID: 2714436     DOI: 10.1016/0014-5793(89)81350-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  17 in total

1.  Molecular diffusion into ferritin: pathways, temperature dependence, incubation time, and concentration effects.

Authors:  X Yang; P Arosio; N D Chasteen
Journal:  Biophys J       Date:  2000-04       Impact factor: 4.033

2.  Facilitated diffusion of iron(II) and dioxygen substrates into human H-chain ferritin. A fluorescence and absorbance study employing the ferroxidase center substitution Y34W.

Authors:  Fadi Bou-Abdallah; Guanghua Zhao; Giorgio Biasiotto; Maura Poli; Paolo Arosio; N Dennis Chasteen
Journal:  J Am Chem Soc       Date:  2008-12-31       Impact factor: 15.419

3.  Calculated electrostatic gradients in recombinant human H-chain ferritin.

Authors:  T Douglas; D R Ripoll
Journal:  Protein Sci       Date:  1998-05       Impact factor: 6.725

4.  Crystal structure of plant ferritin reveals a novel metal binding site that functions as a transit site for metal transfer in ferritin.

Authors:  Taro Masuda; Fumiyuki Goto; Toshihiro Yoshihara; Bunzo Mikami
Journal:  J Biol Chem       Date:  2009-12-09       Impact factor: 5.157

5.  Defining the roles of the threefold channels in iron uptake, iron oxidation and iron-core formation in ferritin: a study aided by site-directed mutagenesis.

Authors:  A Treffry; E R Bauminger; D Hechel; N W Hodson; I Nowik; S J Yewdall; P M Harrison
Journal:  Biochem J       Date:  1993-12-15       Impact factor: 3.857

6.  Spectroscopic identification of the haem axial ligands of haemoferritin and location of possible haem-binding sites in ferritin by molecular modelling.

Authors:  G R Moore; M R Cheesman; F H Kadir; A J Thomson; S J Yewdall; P M Harrison
Journal:  Biochem J       Date:  1992-10-15       Impact factor: 3.857

7.  Amino-acid sequence and predicted three-dimensional structure of pea seed (Pisum sativum) ferritin.

Authors:  S Lobreaux; S J Yewdall; J F Briat; P M Harrison
Journal:  Biochem J       Date:  1992-12-15       Impact factor: 3.857

8.  Iron incorporation into ferritins: evidence for the transfer of monomeric Fe(III) between ferritin molecules and for the formation of an unusual mineral in the ferritin of Escherichia coli.

Authors:  E R Bauminger; A Treffry; A J Hudson; D Hechel; N W Hodson; S C Andrews; S Levi; I Nowik; P Arosio; J R Guest
Journal:  Biochem J       Date:  1994-09-15       Impact factor: 3.857

9.  Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin.

Authors:  S Levi; S J Yewdall; P M Harrison; P Santambrogio; A Cozzi; E Rovida; A Albertini; P Arosio
Journal:  Biochem J       Date:  1992-12-01       Impact factor: 3.857

10.  Iron (II) oxidation and early intermediates of iron-core formation in recombinant human H-chain ferritin.

Authors:  E R Bauminger; P M Harrison; D Hechel; N W Hodson; I Nowik; A Treffry; S J Yewdall
Journal:  Biochem J       Date:  1993-12-15       Impact factor: 3.857

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