Soo-Kyung Cho1,2, Yoon-Kyoung Sung1,2, Chan-Bum Choi1,2, So-Young Bang3, Hoon-Suk Cha4, Jung-Yoon Choe5, Won Tae Chung6, Seung-Jae Hong7, Jae-Bum Jun1, Jinseok Kim8, Tae-Hwan Kim1, Tae-Jong Kim9, Eun-Mi Koh4, Hye-Soon Lee3, Jisoo Lee10, Sang-Heon Lee11, Shin-Seok Lee9, Sung Won Lee6, Sung-Hoon Park5, Dae-Hyun Yoo1, Bo Young Yoon12, Sang-Cheol Bae1,2. 1. a Hanyang University Hospital for Rheumatic Diseases , Seoul , South Korea. 2. b Clinical Research Center for Rheumatoid Arthritis (CRCRA) , Seoul , South Korea. 3. c Hanyang University Guri Hospital , Guri , South Korea. 4. d Sungkyunkwan University School of Medicine, Samsung Medical Center , Seoul , South Korea. 5. e Catholic University of Daegu School of Medicine , Daegu , South Korea. 6. f Dong-A University Hospital , Busan , South Korea. 7. g Kyung Hee University Hospital , Seoul , South Korea. 8. h Jeju National University Hospital , Jeju , South Korea. 9. i Chonnam National University Hospital , Gwangju , South Korea. 10. j Ewha Women's University Mokdong Hospital , Seoul , South Korea. 11. k Konkuk University Medical Center , Seoul , South Korea , and. 12. l Inje University Ilsan Paik Hospital , Goyang , South Korea.
Abstract
OBJECTIVE: To identify the level of agreement between patients with rheumatoid arthritis (RA) and physicians in the global assessment of disease activity and to explore factors influencing their discordance. METHODS: A total of 4368 patients with RA were analyzed from the KORean Observational study Network for Arthritis (KORONA) database. Patients were divided into four subgroups according to difference from their physicians in the assessment of disease activity by substracting physician's visual analog scale (VAS) from patient's VAS as follows: positive discordance group I (10 mm ≤ discordance <25 mm), positive discordance group II (≥25 mm), concordance (<|10| mm), and negative discordance (≤ -10mm). Multinomial logistic regression analysis was performed to identify factors associated with discordance. RESULTS: Only 1350 (29.2%) patients were classified in the concordance group. Positive discordance was found in 52.3% of the patients (n = 2425), with 33.7% (n = 1563) showing marked discordance (≥25 mm). The high disease activity (OR =1.41), gastrointestinal (GI) disease (OR =1.28), pain (OR =1.12), fatigue (OR =1.07) were consistently associated with positive discordance. CONCLUSION: More than half of patients with RA thought their disease more severe than their physicians. In addition to high disease activity, pain, fatigue, and sleep disturbance or GI disease were associated with the discordance between physicians and patients with RA.
OBJECTIVE: To identify the level of agreement between patients with rheumatoid arthritis (RA) and physicians in the global assessment of disease activity and to explore factors influencing their discordance. METHODS: A total of 4368 patients with RA were analyzed from the KORean Observational study Network for Arthritis (KORONA) database. Patients were divided into four subgroups according to difference from their physicians in the assessment of disease activity by substracting physician's visual analog scale (VAS) from patient's VAS as follows: positive discordance group I (10 mm ≤ discordance <25 mm), positive discordance group II (≥25 mm), concordance (<|10| mm), and negative discordance (≤ -10mm). Multinomial logistic regression analysis was performed to identify factors associated with discordance. RESULTS: Only 1350 (29.2%) patients were classified in the concordance group. Positive discordance was found in 52.3% of the patients (n = 2425), with 33.7% (n = 1563) showing marked discordance (≥25 mm). The high disease activity (OR =1.41), gastrointestinal (GI) disease (OR =1.28), pain (OR =1.12), fatigue (OR =1.07) were consistently associated with positive discordance. CONCLUSION: More than half of patients with RA thought their disease more severe than their physicians. In addition to high disease activity, pain, fatigue, and sleep disturbance or GI disease were associated with the discordance between physicians and patients with RA.
Entities:
Keywords:
Arthritis; Discordance; Fatigue; Gastrointestinal diseases; Pain; Patient global assessment; Physician global assessment; Rheumatoid; Sleep
Authors: Maria Fernanda Brandão Resende Guimarães; Maria Raquel da Costa Pinto; Gustavo Gomes Resende; Carla Jorge Machado; Ana Beatriz Vargas-Santos; Rodrigo Balbino Chaves Amorim; Ana Paula Monteiro Gomides; Cleandro Pires de Albuquerque; Manoel Barros Bértolo; Paulo Louzada Júnior; Isabela Araújo Santos; Rina Dalva Neubarth Giorgi; Nathalia de Carvalho Saciloto; Sebastião Cezar Radominski; Fernanda Maria Borghi; Karina Rossi Bonfiglioli; Henrique Carriço da Silva; Maria de Fátima L da Cunha Sauma; Marcel Lobato Sauma; Júlia Brito de Medeiros; Ivânio Alves Pereira; Gláucio Ricardo Werner de Castro; Claiton Viegas Brenol; Ricardo Machado Xavier; Licia Maria Henrique Mota; Geraldo da Rocha Castelar-Pinheiro Journal: PLoS One Date: 2020-03-13 Impact factor: 3.240
Authors: Lewis Carpenter; Elena Nikiphorou; Patrick D W Kiely; David A Walsh; Adam Young; Sam Norton Journal: Rheumatology (Oxford) Date: 2020-09-01 Impact factor: 7.580