Literature DB >> 27141961

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update.

Maxim V Kuleshov1, Matthew R Jones1, Andrew D Rouillard1, Nicolas F Fernandez1, Qiaonan Duan1, Zichen Wang1, Simon Koplev1, Sherry L Jenkins1, Kathleen M Jagodnik2, Alexander Lachmann1, Michael G McDermott1, Caroline D Monteiro1, Gregory W Gundersen1, Avi Ma'ayan3.   

Abstract

Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libraries available for analysis and download. In total, Enrichr currently contains 180 184 annotated gene sets from 102 gene set libraries. New features have been added to Enrichr including the ability to submit fuzzy sets, upload BED files, improved application programming interface and visualization of the results as clustergrams. Overall, Enrichr is a comprehensive resource for curated gene sets and a search engine that accumulates biological knowledge for further biological discoveries. Enrichr is freely available at: http://amp.pharm.mssm.edu/Enrichr.
© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

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Year:  2016        PMID： 27141961      PMCID： PMC4987924          DOI： 10.1093/nar/gkw377

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


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