Literature DB >> 27141338

Novel understanding of self-reactive T cells.

Mads Hald Andersen1.   

Abstract

In a recent issue of Immunity, Mark Davis and colleagues describe that thymic selection does not eliminate but prunes self-reactive T cell clones. Self-reactive T cells are a natural part of the T-cell repertoire and may be important in the fight against pathogens in addition to being important immune regulators.

Entities:  

Keywords:  Anti-Tregs; CD8; IDO; PD-L1; self-reactive T cells; thymic selection

Year:  2015        PMID： 27141338      PMCID： PMC4839311          DOI： 10.1080/2162402X.2015.1083672

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

1.  Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators.

Authors:  Rikke Baek Sørensen; Sine Reker Hadrup; Inge Marie Svane; Mads Christian Hjortsø; Per Thor Straten; Mads Hald Andersen
Journal:  Blood       Date:  2010-11-15       Impact factor: 22.113

2.  Immune Regulation by Self-Recognition: Novel Possibilities for Anticancer Immunotherapy.

Authors:  Mads Hald Andersen
Journal:  J Natl Cancer Inst       Date:  2015-06-10       Impact factor: 13.506

3.  Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T Lymphocytes.

Authors:  Wong Yu; Ning Jiang; Peter J R Ebert; Brian A Kidd; Sabina Müller; Peder J Lund; Jeremy Juang; Keishi Adachi; Tiffany Tse; Michael E Birnbaum; Evan W Newell; Darrell M Wilson; Gijsbert M Grotenbreg; Salvatore Valitutti; Stephen R Quake; Mark M Davis
Journal:  Immunity       Date:  2015-05-19       Impact factor: 31.745

4.  HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients.

Authors:  Shamaila Munir; Gitte Holmen Andersen; Özcan Met; Marco Donia; Thomas Mørch Frøsig; Stine Kiaer Larsen; Tobias Wirenfeldt Klausen; Inge Marie Svane; Mads Hald Andersen
Journal:  Cancer Res       Date:  2013-01-17       Impact factor: 12.701

5.  Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10.

Authors:  Martin J Raftery; Dörte Wieland; Stefanie Gronewald; Annette A Kraus; Thomas Giese; Günther Schönrich
Journal:  J Immunol       Date:  2004-09-01       Impact factor: 5.422

Review 6.  The targeting of immunosuppressive mechanisms in hematological malignancies.

Authors:  M H Andersen
Journal:  Leukemia       Date:  2014-03-18       Impact factor: 11.528

7.  Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.

Authors:  Shamaila Munir; Stine Kiaer Larsen; Trine Zeeberg Iversen; Marco Donia; Tobias Wirenfeldt Klausen; Inge Marie Svane; Per Thor Straten; Mads Hald Andersen
Journal:  PLoS One       Date:  2012-04-23       Impact factor: 3.240

8.  CD4 responses against IDO.

Authors:  Mads Hald Andersen
Journal:  Oncoimmunology       Date:  2012-10-01       Impact factor: 8.110

9.  The immune checkpoint regulator PD-L1 is a specific target for naturally occurring CD4+ T cells.

Authors:  Shamaila Munir; Gitte Holmen Andersen; Inge Marie Svane; Mads Hald Andersen
Journal:  Oncoimmunology       Date:  2013-04-01       Impact factor: 8.110

10.  The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease.

Authors:  V Kumar; E E Sercarz
Journal:  J Exp Med       Date:  1993-09-01       Impact factor: 14.307
  10 in total
  2 in total

Review 1.  Recent advances in CD8+ regulatory T cell research.

Authors:  Yating Yu; Xinbo Ma; Rufei Gong; Jianmeng Zhu; Lihua Wei; Jinguang Yao
Journal:  Oncol Lett       Date:  2018-03-29       Impact factor: 2.967

Review 2.  Natural Compounds with Potential to Modulate Cancer Therapies and Self-Reactive Immune Cells.

Authors:  Rhiane Moody; Kirsty Wilson; Anthony Jaworowski; Magdalena Plebanski
Journal:  Cancers (Basel)       Date:  2020-03-13       Impact factor: 6.639
  2 in total

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