Literature DB >> 27141051

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.

Masato Morikawa1, Rik Derynck2, Kohei Miyazono3.   

Abstract

The transforming growth factor-β (TGF-β) is the prototype of the TGF-β family of growth and differentiation factors, which is encoded by 33 genes in mammals and comprises homo- and heterodimers. This review introduces the reader to the TGF-β family with its complexity of names and biological activities. It also introduces TGF-β as the best-studied factor among the TGF-β family proteins, with its diversity of roles in the control of cell proliferation and differentiation, wound healing and immune system, and its key roles in pathology, for example, skeletal diseases, fibrosis, and cancer.
Copyright © 2016 Cold Spring Harbor Laboratory Press; all rights reserved.

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Year:  2016        PMID： 27141051      PMCID： PMC4852809          DOI： 10.1101/cshperspect.a021873

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Biol        ISSN： 1943-0264            Impact factor:   10.005


  218 in total

1.  Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos.

Authors:  W C Smith; R M Harland
Journal:  Cell       Date:  1992-09-04       Impact factor: 41.582

2.  Simultaneous suppression of TGF-β and ERK signaling contributes to the highly efficient and reproducible generation of mouse embryonic stem cells from previously considered refractory and non-permissive strains.

Authors:  Seyedeh-Nafiseh Hassani; Mehdi Totonchi; Ali Farrokhi; Adeleh Taei; Mehran Rezaei Larijani; Hamid Gourabi; Hossein Baharvand
Journal:  Stem Cell Rev Rep       Date:  2012-06       Impact factor: 5.739

3.  Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.

Authors:  S Paul Oh; Chang-Yeol Yeo; Youngjae Lee; Heindrich Schrewe; Malcolm Whitman; En Li
Journal:  Genes Dev       Date:  2002-11-01       Impact factor: 11.361

4.  Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.

Authors:  Laurent David; Christine Mallet; Sabine Mazerbourg; Jean-Jacques Feige; Sabine Bailly
Journal:  Blood       Date:  2006-10-26       Impact factor: 22.113

Review 5.  Lessons from the cancer genome.

Authors:  Levi A Garraway; Eric S Lander
Journal:  Cell       Date:  2013-03-28       Impact factor: 41.582

6.  Crystal structure of BMP-9 and functional interactions with pro-region and receptors.

Authors:  Monica A Brown; Qinghai Zhao; Kent A Baker; Chethana Naik; Cecil Chen; Laurie Pukac; Mallika Singh; Tatiana Tsareva; Yanick Parice; Angela Mahoney; Viktor Roschke; Indra Sanyal; Senyon Choe
Journal:  J Biol Chem       Date:  2005-04-25       Impact factor: 5.157

7.  Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases.

Authors:  Neil M Wolfman; Alexandra C McPherron; William N Pappano; Monique V Davies; Kening Song; Kathleen N Tomkinson; Jill F Wright; Liz Zhao; Suzanne M Sebald; Daniel S Greenspan; Se-Jin Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-11       Impact factor: 11.205

8.  Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy.

Authors:  Francesco S Loffredo; Matthew L Steinhauser; Steven M Jay; Joseph Gannon; James R Pancoast; Pratyusha Yalamanchi; Manisha Sinha; Claudia Dall'Osso; Danika Khong; Jennifer L Shadrach; Christine M Miller; Britta S Singer; Alex Stewart; Nikolaos Psychogios; Robert E Gerszten; Adam J Hartigan; Mi-Jeong Kim; Thomas Serwold; Amy J Wagers; Richard T Lee
Journal:  Cell       Date:  2013-05-09       Impact factor: 41.582

9.  Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

Authors:  D R Edwards; G Murphy; J J Reynolds; S E Whitham; A J Docherty; P Angel; J K Heath
Journal:  EMBO J       Date:  1987-07       Impact factor: 11.598

10.  Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega.

Authors:  Fabian Sievers; Andreas Wilm; David Dineen; Toby J Gibson; Kevin Karplus; Weizhong Li; Rodrigo Lopez; Hamish McWilliam; Michael Remmert; Johannes Söding; Julie D Thompson; Desmond G Higgins
Journal:  Mol Syst Biol       Date:  2011-10-11       Impact factor: 11.429
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  305 in total

1.  Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition.

Authors:  Yoko Katsuno; Dominique Stephan Meyer; Ziyang Zhang; Kevan M Shokat; Rosemary J Akhurst; Kohei Miyazono; Rik Derynck
Journal:  Sci Signal       Date:  2019-02-26       Impact factor: 8.192

2.  Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.

Authors:  Maiko Omi; Vesa Kaartinen; Yuji Mishina
Journal:  J Biol Chem       Date:  2019-10-16       Impact factor: 5.157

3.  Islet transplantation attenuates cardiac fibrosis in diabetic rats through inhibition of TGF-β1/Smad3 pathway.

Authors:  Hong-Wei Wang; Yi-He Chen; Yan-Yan Chen; Wei Huang; Xian-Dong Zhu; Fu-Biao Ni; Guo-Di Wu; Zi-Qiang Xu; Zhou-Qing Huang; Bi-Cheng Chen; Fang-Yi Xiao
Journal:  Am J Transl Res       Date:  2018-08-15       Impact factor: 4.060

4.  Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway.

Authors:  Liu-Ya Tang; Mary Heller; Zhaojing Meng; Li-Rong Yu; Yi Tang; Ming Zhou; Ying E Zhang
Journal:  J Biol Chem       Date:  2017-01-31       Impact factor: 5.157

5.  Relationship Between the Efficacy of Cardiac Cell Therapy and the Inhibition of Differentiation of Human iPSC-Derived Nonmyocyte Cardiac Cells Into Myofibroblast-Like Cells.

Authors:  Ling Gao; Libang Yang; Lu Wang; Zhaohui Geng; Yuhua Wei; Glenn Gourley; Jianyi Zhang
Journal:  Circ Res       Date:  2018-12-07       Impact factor: 17.367

Review 6.  Specificity, versatility, and control of TGF-β family signaling.

Authors:  Rik Derynck; Erine H Budi
Journal:  Sci Signal       Date:  2019-02-26       Impact factor: 8.192

Review 7.  The role of transforming growth factor (TGF)-β in the infarcted myocardium.

Authors:  Nikolaos G Frangogiannis
Journal:  J Thorac Dis       Date:  2017-03       Impact factor: 2.895

Review 8.  TGF-β Family Signaling in Mesenchymal Differentiation.

Authors:  Ingo Grafe; Stefanie Alexander; Jonathan R Peterson; Taylor Nicholas Snider; Benjamin Levi; Brendan Lee; Yuji Mishina
Journal:  Cold Spring Harb Perspect Biol       Date:  2018-05-01       Impact factor: 10.005

9.  The regulatory protein SnoN antagonizes activin/Smad2 protein signaling and thereby promotes adipocyte differentiation and obesity in mice.

Authors:  Qingwei Zhu; Amanda Chang; Albert Xu; Kunxin Luo
Journal:  J Biol Chem       Date:  2018-07-20       Impact factor: 5.157

Review 10.  Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation.

Authors:  Tyler A Beach; Angela M Groves; Jacqueline P Williams; Jacob N Finkelstein
Journal:  Int J Radiat Biol       Date:  2018-10-25       Impact factor: 2.694
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