John M Carethers1, Ajay Goel2. 1. Division of Gastroenterology, Department of Internal Medicine, Department of Human Genetics, and the University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Electronic address: jcarethe@umich.edu. 2. Center for Gastrointestinal Research, Center for Epigenetics, Cancer Prevention and Cancer Genomics, Baylor Research Institute and Charles A. Sammons Cancer Center, Baylor University Medical Center, Dallas, Texas.