Literature DB >> 27138562

PD-1 Shapes B Cells as Evildoers in the Tumor Microenvironment.

Zhenhua Ren1, Hua Peng2, Yang-Xin Fu3.   

Abstract

Protumorigenic PD-1(hi) B cells, induced in hepatocellular carcinoma, suppress tumor-specific T-cell response via IL10-dependent pathways upon PD-1/PD-L1 interaction. Anti-PD-1 or anti-PD-L1 antibodies may function not only through blocking the PD-1 coinhibitory pathway in T cells but also via abolishing the suppressive function of regulatory B cells. Cancer Discov; 6(5); 477-8. ©2016 AACRSee related article by Xiao et al., p. 546. ©2016 American Association for Cancer Research.

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Year:  2016        PMID： 27138562      PMCID： PMC4856221          DOI： 10.1158/2159-8290.CD-16-0307

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  10 in total

1.  B cells inhibit induction of T cell-dependent tumor immunity.

Authors:  Z Qin; G Richter; T Schüler; S Ibe; X Cao; T Blankenstein
Journal:  Nat Med       Date:  1998-05       Impact factor: 53.440

Review 2.  Regulatory B cells in anti-tumor immunity.

Authors:  Yu Zhang; Nicolas Gallastegui; Joseph D Rosenblatt
Journal:  Int Immunol       Date:  2015-05-20       Impact factor: 4.823

3.  PD-1hi Identifies a Novel Regulatory B-cell Population in Human Hepatoma That Promotes Disease Progression.

Authors:  Xiao Xiao; Xiang-Ming Lao; Min-Min Chen; Rui-Xian Liu; Yuan Wei; Fang-Zhu Ouyang; Dong-Ping Chen; Xiao-Yu Zhao; Qiyi Zhao; Xue-Feng Li; Chuan-Lu Liu; Limin Zheng; Dong-Ming Kuang
Journal:  Cancer Discov       Date:  2016-02-29       Impact factor: 39.397

4.  B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas.

Authors:  Nesrine I Affara; Brian Ruffell; Terry R Medler; Andrew J Gunderson; Magnus Johansson; Sophia Bornstein; Emily Bergsland; Martin Steinhoff; Yijin Li; Qian Gong; Yan Ma; Jane F Wiesen; Melissa H Wong; Molly Kulesz-Martin; Bryan Irving; Lisa M Coussens
Journal:  Cancer Cell       Date:  2014-06-05       Impact factor: 31.743

5.  B Cells Promote Pancreatic Tumorigenesis.

Authors:  Ali Roghanian; Christopher Fraser; Marianna Kleyman; Jianzhu Chen
Journal:  Cancer Discov       Date:  2016-03       Impact factor: 39.397

6.  Tumor-evoked regulatory B cells promote breast cancer metastasis by converting resting CD4⁺ T cells to T-regulatory cells.

Authors:  Purevdorj B Olkhanud; Bazarragchaa Damdinsuren; Monica Bodogai; Ronald E Gress; Ranjan Sen; Katarzyna Wejksza; Enkhzol Malchinkhuu; Robert P Wersto; Arya Biragyn
Journal:  Cancer Res       Date:  2011-03-28       Impact factor: 12.701

7.  B cells regulate autoimmunity by provision of IL-10.

Authors:  Simon Fillatreau; Claire H Sweenie; Mandy J McGeachy; David Gray; Stephen M Anderton
Journal:  Nat Immunol       Date:  2002-09-03       Impact factor: 25.606

Review 8.  PD-1 and its ligands in tolerance and immunity.

Authors:  Mary E Keir; Manish J Butte; Gordon J Freeman; Arlene H Sharpe
Journal:  Annu Rev Immunol       Date:  2008       Impact factor: 28.527

Review 9.  PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations.

Authors:  Weiping Zou; Jedd D Wolchok; Lieping Chen
Journal:  Sci Transl Med       Date:  2016-03-02       Impact factor: 17.956

10.  Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice.

Authors:  S D Wolf; B N Dittel; F Hardardottir; C A Janeway
Journal:  J Exp Med       Date:  1996-12-01       Impact factor: 14.307
  10 in total
  13 in total

1.  Macrophage regulation of B cell proliferation.

Authors:  Naomi Goldman; Kornelija Valiuskyte; Jennifer Londregan; Adam Swider; John Somerville; James E Riggs
Journal:  Cell Immunol       Date:  2017-02-21       Impact factor: 4.868

2.  Identification of a Recurrence Gene Signature for Ovarian Cancer Prognosis by Integrating Single-Cell RNA Sequencing and Bulk Expression Datasets.

Authors:  Yongjian Zhang; Wei Huang; Dejia Chen; Yue Zhao; Fusheng Sun; Zhiqiang Wang; Ge Lou
Journal:  Front Genet       Date:  2022-06-08       Impact factor: 4.772

3.  Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer.

Authors:  Andrew H Ko; Alexander C Jordan; Evan Tooker; Simon F Lacey; Renee B Chang; Yan Li; Alan P Venook; Margaret Tempero; Lloyd Damon; Lawrence Fong; Mark H O'Hara; Bruce L Levine; J Joseph Melenhorst; Gabriela Plesa; Carl H June; Gregory L Beatty
Journal:  Mol Ther       Date:  2020-07-21       Impact factor: 11.454

4.  Tumor infiltrating CD19+ B lymphocytes predict prognostic and therapeutic benefits in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors.

Authors:  Zhiyuan Lin; Li Liu; Yu Xia; Xiang Chen; Ying Xiong; Yang Qu; Jiajun Wang; Qi Bai; Jianming Guo; Jiejie Xu
Journal:  Oncoimmunology       Date:  2018-08-06       Impact factor: 8.110

5.  A novel MDSC-induced PD-1-PD-L1+ B-cell subset in breast tumor microenvironment possesses immuno-suppressive properties.

Authors:  Meng Shen; Jian Wang; Wenwen Yu; Chen Zhang; Min Liu; Kaiyuan Wang; Lili Yang; Feng Wei; Shizhen Emily Wang; Qian Sun; Xiubao Ren
Journal:  Oncoimmunology       Date:  2018-02-20       Impact factor: 8.110

Review 6.  Harnessing immunotherapy for liver recipients with hepatocellular carcinoma: a review from a transplant oncology perspective.

Authors:  Cheng-Maw Ho; Hui-Ling Chen; Rey-Heng Hu; Po-Huang Lee
Journal:  Ther Adv Med Oncol       Date:  2019-04-26       Impact factor: 8.168

7.  Circulating exosomes from esophageal squamous cell carcinoma mediate the generation of B10 and PD-1high Breg cells.

Authors:  Yu Mao; Yimin Wang; Lixin Dong; Qiang Zhang; Chao Wang; Yanqiu Zhang; Xin Li; Zhanzhao Fu
Journal:  Cancer Sci       Date:  2019-07-28       Impact factor: 6.716

8.  Molecular and Clinical Characterization of PD-1 in Breast Cancer Using Large-Scale Transcriptome Data.

Authors:  Qiang Liu; Ran Cheng; Xiangyi Kong; Zhongzhao Wang; Yi Fang; Jing Wang
Journal:  Front Immunol       Date:  2020-11-17       Impact factor: 7.561

9.  Dying cells expose a nuclear antigen cross-reacting with anti-PD-1 monoclonal antibodies.

Authors:  Philipp Metzger; Sabrina V Kirchleitner; Lars M Koenig; Christine Hörth; Sebastian Kobold; Stefan Endres; Max Schnurr; Peter Duewell
Journal:  Sci Rep       Date:  2018-06-11       Impact factor: 4.379

Review 10.  Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery.

Authors:  Eric de Sousa; Joana R Lérias; Antonio Beltran; Georgia Paraschoudi; Carolina Condeço; Jéssica Kamiki; Patrícia Alexandra António; Nuno Figueiredo; Carlos Carvalho; Mireia Castillo-Martin; Zhe Wang; Dário Ligeiro; Martin Rao; Markus Maeurer
Journal:  Front Immunol       Date:  2021-07-15       Impact factor: 7.561
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