Literature DB >> 27138561

MENA Promotes Tumor-Intrinsic Metastasis through ECM Remodeling and Haptotaxis.

Miguel Santiago-Medina1, Jing Yang2.   

Abstract

Oudin and colleagues report a novel and specific function of MENA in mediating directional migration of breast cancer cells toward a fibronectin gradient of increasing concentration. This MENA-mediated haptotactic response depends on the binding of MENA to the α5β1 integrin receptor, adhesion protein signaling, and fibronectin fibrillogenesis. Cancer Discov; 6(5); 474-6. ©2016 AACRSee related article by Oudin et al., p. 516. ©2016 American Association for Cancer Research.

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Year:  2016        PMID： 27138561      PMCID： PMC4856219          DOI： 10.1158/2159-8290.CD-16-0231

Source DB:  PubMed          Journal:  Cancer Discov        ISSN： 2159-8274            Impact factor:   39.397


  10 in total

1.  Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex.

Authors:  S Krugmann; I Jordens; K Gevaert; M Driessens; J Vandekerckhove; A Hall
Journal:  Curr Biol       Date:  2001-10-30       Impact factor: 10.834

2.  Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways.

Authors:  S Aznavoorian; M L Stracke; J Parsons; J McClanahan; L A Liotta
Journal:  J Biol Chem       Date:  1996-02-09       Impact factor: 5.157

3.  Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer.

Authors:  Evanthia T Roussos; Michele Balsamo; Shannon K Alford; Jeffrey B Wyckoff; Bojana Gligorijevic; Yarong Wang; Maria Pozzuto; Robert Stobezki; Sumanta Goswami; Jeffrey E Segall; Douglas A Lauffenburger; Anne R Bresnick; Frank B Gertler; John S Condeelis
Journal:  J Cell Sci       Date:  2011-07-01       Impact factor: 5.285

4.  Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro.

Authors:  J B McCarthy; L T Furcht
Journal:  J Cell Biol       Date:  1984-04       Impact factor: 10.539

5.  Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer.

Authors:  Young Kyung Bae; Aeri Kim; Min Kyoung Kim; Jung Eun Choi; Su Hwan Kang; Soo Jung Lee
Journal:  Hum Pathol       Date:  2013-05-14       Impact factor: 3.466

6.  Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system.

Authors:  Torsten Giesemann; Günter Schwarz; Ralph Nawrotzki; Kerstin Berhörster; Martin Rothkegel; Kathrin Schlüter; Nils Schrader; Hermann Schindelin; Ralf R Mendel; Joachim Kirsch; Brigitte M Jockusch
Journal:  J Neurosci       Date:  2003-09-10       Impact factor: 6.167

7.  Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis.

Authors:  Sophie Astrof; Denise Crowley; Elizabeth L George; Tomohiko Fukuda; Kiyotoshi Sekiguchi; Douglas Hanahan; Richard O Hynes
Journal:  Mol Cell Biol       Date:  2004-10       Impact factor: 4.272

8.  Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Authors:  Madeleine J Oudin; Oliver Jonas; Tatsiana Kosciuk; Liliane C Broye; Bruna C Guido; Jeff Wyckoff; Daisy Riquelme; John M Lamar; Sreeja B Asokan; Charlie Whittaker; Duanduan Ma; Robert Langer; Michael J Cima; Kari B Wisinski; Richard O Hynes; Douglas A Lauffenburger; Patricia J Keely; James E Bear; Frank B Gertler
Journal:  Cancer Discov       Date:  2016-01-25       Impact factor: 39.397

9.  LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues.

Authors:  Keefe T Chan; Sreeja B Asokan; Samantha J King; Tao Bo; Evan S Dubose; Wenjin Liu; Matthew E Berginski; Jeremy M Simon; Ian J Davis; Shawn M Gomez; Norman E Sharpless; James E Bear
Journal:  J Cell Biol       Date:  2014-10-27       Impact factor: 10.539

10.  A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis.

Authors:  Ulrike Philippar; Evanthia T Roussos; Matthew Oser; Hideki Yamaguchi; Hyung-Do Kim; Silvia Giampieri; Yarong Wang; Sumanta Goswami; Jeffrey B Wyckoff; Douglas A Lauffenburger; Erik Sahai; John S Condeelis; Frank B Gertler
Journal:  Dev Cell       Date:  2008-12       Impact factor: 12.270
  10 in total
  8 in total

1.  Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.

Authors:  Ting Yan; Ailiang Zhang; Fangfang Shi; Fei Chang; Jie Mei; Yongjian Liu; Yichao Zhu
Journal:  J Biol Chem       Date:  2018-05-11       Impact factor: 5.157

Review 2.  For robust big data analyses: a collection of 150 important pro-metastatic genes.

Authors:  Yan Mei; Jun-Ping Yang; Chao-Nan Qian
Journal:  Chin J Cancer       Date:  2017-01-21

3.  Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer.

Authors:  Qinglei Gao; Zongyuan Yang; Sen Xu; Xiaoting Li; Xin Yang; Ping Jin; Yi Liu; Xiaoshui Zhou; Taoran Zhang; Cheng Gong; Xiao Wei; Dan Liu; Chaoyang Sun; Gang Chen; Junbo Hu; Li Meng; Jianfeng Zhou; Kenjiro Sawada; Robert Fruscio; Thomas W Grunt; Jörg Wischhusen; Víctor Manuel Vargas-Hernández; Bhavana Pothuri; Robert L Coleman
Journal:  J Exp Med       Date:  2019-02-01       Impact factor: 14.307

4.  LOXL 2 Promotes The Epithelial-Mesenchymal Transition And Malignant Progression Of Cervical Cancer.

Authors:  Jing Tian; He-Xi Sun; Ying-Chun Li; Li Jiang; Shan-Ling Zhang; Quan Hao
Journal:  Onco Targets Ther       Date:  2019-10-30       Impact factor: 4.147

Review 5.  Cancer-Associated Fibroblasts: Mechanisms of Tumor Progression and Novel Therapeutic Targets.

Authors:  Ralf-Peter Czekay; Dong-Joo Cheon; Rohan Samarakoon; Stacie M Kutz; Paul J Higgins
Journal:  Cancers (Basel)       Date:  2022-02-27       Impact factor: 6.639

6.  Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.

Authors:  Aida Barreiro-Alonso; Mónica Lamas-Maceiras; Rosa García-Díaz; Esther Rodríguez-Belmonte; Lu Yu; Mercedes Pardo; Jyoti S Choudhary; María Esperanza Cerdán
Journal:  Oncotarget       Date:  2018-04-10

Review 7.  Fibronectin in Cancer: Friend or Foe.

Authors:  Tsung-Cheng Lin; Cheng-Han Yang; Li-Hsin Cheng; Wen-Tsan Chang; Yuh-Rong Lin; Hung-Chi Cheng
Journal:  Cells       Date:  2019-12-20       Impact factor: 6.600

8.  Comparative proteomic analysis of different stages of breast cancer tissues using ultra high performance liquid chromatography tandem mass spectrometer.

Authors:  Abdullah Saleh Al-Wajeeh; Salizawati Muhamad Salhimi; Majed Ahmed Al-Mansoub; Imran Abdul Khalid; Thomas Michael Harvey; Aishah Latiff; Mohd Nazri Ismail
Journal:  PLoS One       Date:  2020-01-16       Impact factor: 3.240
  8 in total

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