| Literature DB >> 27137794 |
Jeanine M M van Klink1, Hendrik M Koopman2, Monique Rijken1, Johanna M Middeldorp3, Dick Oepkes3, Enrico Lopriore1.
Abstract
Twin-twin transfusion syndrome (TTTS) is a severe complication of monochorionic (MC) twin pregnancies associated with high perinatal mortality and morbidity rates. Management in TTTS is a major challenge for obstetricians and neonatologists. Twins with TTTS are often born prematurely after an extremely distressing and highly hazardous fetal period. Follow-up studies report varying rates of cerebral palsy (CP) and long-term neurodevelopmental impairment (NDI). This review discusses the latest findings on the long-term outcome of TTTS survivors, possible risk factors for long-term impairment, and provides recommendations for future research.Entities:
Keywords: amnioreduction; laser surgery; monochorionic twins; neurodevelopmental outcome; twin–twin transfusion syndrome
Mesh:
Year: 2016 PMID: 27137794 DOI: 10.1017/thg.2016.26
Source DB: PubMed Journal: Twin Res Hum Genet ISSN: 1832-4274 Impact factor: 1.587