Literature DB >> 27137097

Secreted fungal aspartic proteases: A review.

Virginia Mandujano-González1, Lourdes Villa-Tanaca2, Miguel Angel Anducho-Reyes1, Yuridia Mercado-Flores3.   

Abstract

The aspartic proteases, also called aspartyl and aspartate proteases or acid proteases (E.C.3.4.23), belong to the endopeptidase family and are characterized by the conserved sequence Asp-Gly-Thr at the active site. These enzymes are found in a wide variety of microorganisms in which they perform important functions related to nutrition and pathogenesis. In addition, their high activity and stability at acid pH make them attractive for industrial application in the food industry; specifically, they are used as milk-coagulating agents in cheese production or serve to improve the taste of some foods. This review presents an analysis of the characteristics and properties of secreted microbial aspartic proteases and their potential for commercial application.
Copyright © 2016 Asociación Española de Micología. Published by Elsevier Espana. All rights reserved.

Entities:  

Keywords:  Aspartil-proteasas secretadas; E.C.3.4.23; Enzimas fúngicas; Fungal enzymes; Secreted aspartic proteases

Mesh：

Substances：

Year:  2016        PMID： 27137097     DOI： 10.1016/j.riam.2015.10.003

Source DB:  PubMed          Journal:  Rev Iberoam Micol        ISSN： 1130-1406            Impact factor:   1.044


  9 in total

1.  Heterologous expression and characterization of the aspartic endoprotease Pep4um from Ustilago maydis, a homolog of the human Chatepsin D, an important breast cancer therapeutic target.

Authors:  Margarita Juárez-Montiel; Pedro Tesillo-Moreno; Ana Cruz-Angeles; Valentina Soberanes-Gutiérrez; Griselda Chávez-Camarillo; J Antonio Ibarra; César Hernández-Rodríguez; Lourdes Villa-Tanaca
Journal:  Mol Biol Rep       Date:  2018-08-03       Impact factor: 2.316

2.  Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor.

Authors:  Pollyanna Stephanie Gomes; Monique Pacheco Duarte Carneiro; Patrícia de Almeida Machado; Valter Viana de Andrade-Neto; Alessandra Marcia da Fonseca-Martins; Amy Goundry; João Vitor Marques Pereira da Silva; Daniel Claudio Oliveira Gomes; Ana Paula Cabral de Araujo Lima; Vítor Ennes-Vidal; Ana Carolina Rennó Sodero; Salvatore Giovanni De-Simone; Herbert L de Matos Guedes
Journal:  Curr Issues Mol Biol       Date:  2022-05-09       Impact factor: 2.976

3.  Site-specific cleavage of bacterial MucD by secreted proteases mediates antibacterial resistance in Arabidopsis.

Authors:  Yiming Wang; Ruben Garrido-Oter; Jingni Wu; Thomas M Winkelmüller; Matthew Agler; Thomas Colby; Tatsuya Nobori; Eric Kemen; Kenichi Tsuda
Journal:  Nat Commun       Date:  2019-06-28       Impact factor: 14.919

4.  Aspartic peptidase of Phialophora verrucosa as target of HIV peptidase inhibitors: blockage of its enzymatic activity and interference with fungal growth and macrophage interaction.

Authors:  Marcela Q Granato; Ingrid S Sousa; Thabatta L S A Rosa; Diego S Gonçalves; Sergio H Seabra; Daniela S Alviano; Maria C V Pessolani; André L S Santos; Lucimar F Kneipp
Journal:  J Enzyme Inhib Med Chem       Date:  2020-12       Impact factor: 5.051

5.  In silico Proteomic Analysis Provides Insights Into Phylogenomics and Plant Biomass Deconstruction Potentials of the Tremelalles.

Authors:  Habibu Aliyu; Olga Gorte; Xinhai Zhou; Anke Neumann; Katrin Ochsenreither
Journal:  Front Bioeng Biotechnol       Date:  2020-04-03

6.  Bioinformatic mapping of a more precise Aspergillus niger degradome.

Authors:  Zixing Dong; Shuangshuang Yang; Byong H Lee
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.379

Review 7.  Fungal Proteases as Emerging Biocatalysts to Meet the Current Challenges and Recent Developments in Biomedical Therapies: An Updated Review.

Authors:  Muhammad Naeem; Saba Manzoor; Mashhud-Ul-Hasan Abid; Muhammad Burhan Khan Tareen; Mirza Asad; Sajida Mushtaq; Nazia Ehsan; Dua Amna; Baojun Xu; Abu Hazafa
Journal:  J Fungi (Basel)       Date:  2022-01-24

8.  Genomes and secretomes of Ascomycota fungi reveal diverse functions in plant biomass decomposition and pathogenesis.

Authors:  Jean F Challacombe; Cedar N Hesse; Lisa M Bramer; Lee Ann McCue; Mary Lipton; Samuel Purvine; Carrie Nicora; La Verne Gallegos-Graves; Andrea Porras-Alfaro; Cheryl R Kuske
Journal:  BMC Genomics       Date:  2019-12-12       Impact factor: 3.969

Review 9.  Plant Milk-Clotting Enzymes for Cheesemaking.

Authors:  Fabrizio Domenico Nicosia; Ivana Puglisi; Alessandra Pino; Cinzia Caggia; Cinzia Lucia Randazzo
Journal:  Foods       Date:  2022-03-18
  9 in total

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