Sakiko Soutome1, Souichi Yanamoto2, Madoka Funahara2, Takumi Hasegawa3, Takahide Komori3, Takahiko Oho4, Masahiro Umeda2. 1. 1 Perioperative Oral Management Center, Nagasaki University Hospital , Nagasaki, Japan . 2. 2 Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Sciences , Nagasaki, Japan . 3. 3 Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine , Kobe, Japan . 4. 4 Department of Preventive Dentistry, Kagoshima University Graduate School of Medical and Dental Sciences , Kagoshima, Japan .
Abstract
BACKGROUND: Post-operative pneumonia is a frequent and possibly fatal complication of esophagectomy and is likely caused by aspiration of oropharyngeal fluid that contains pathogenic micro-organisms. We conducted a multi-center retrospective study to investigate the preventive effect of oral health care on post-operative pneumonia among patients with esophageal cancer who underwent esophagectomy. METHODS: A total of 280 patients underwent esophagectomy at three university hospitals. These patients were divided retrospectively into those who received pre-operative oral care from dentists and dental hygienists (oral care group; n = 173) and those who did not receive such care (control group; n = 107). We evaluated the correlations between the occurrence of post-operative pneumonia and 18 predictive variables (patient factors, tumor factors, treatment factors, and pre-operative oral care) using the χ(2) test and logistic regression analysis. The differences of mean hospital days and mortality rate in both groups were analyzed by the Student t-test. RESULTS: Age, post-operative dysphagia, and absence of pre-operative oral care were correlated significantly with post-operative pneumonia in the univariable analysis. Multivariable analysis revealed that diabetes mellitus, post-operative dysphagia, and the absence of pre-operative oral care were independent risk factors for post-operative pneumonia. The mean hospital stay and mortality rate did not differ between the oral care and control groups. CONCLUSION: Pre-operative oral care may be an effective and easy method to prevent post-operative pneumonia in patients who are undergoing esophagectomy.
BACKGROUND: Post-operative pneumonia is a frequent and possibly fatal complication of esophagectomy and is likely caused by aspiration of oropharyngeal fluid that contains pathogenic micro-organisms. We conducted a multi-center retrospective study to investigate the preventive effect of oral health care on post-operative pneumonia among patients with esophageal cancer who underwent esophagectomy. METHODS: A total of 280 patients underwent esophagectomy at three university hospitals. These patients were divided retrospectively into those who received pre-operative oral care from dentists and dental hygienists (oral care group; n = 173) and those who did not receive such care (control group; n = 107). We evaluated the correlations between the occurrence of post-operative pneumonia and 18 predictive variables (patient factors, tumor factors, treatment factors, and pre-operative oral care) using the χ(2) test and logistic regression analysis. The differences of mean hospital days and mortality rate in both groups were analyzed by the Student t-test. RESULTS: Age, post-operative dysphagia, and absence of pre-operative oral care were correlated significantly with post-operative pneumonia in the univariable analysis. Multivariable analysis revealed that diabetes mellitus, post-operative dysphagia, and the absence of pre-operative oral care were independent risk factors for post-operative pneumonia. The mean hospital stay and mortality rate did not differ between the oral care and control groups. CONCLUSION: Pre-operative oral care may be an effective and easy method to prevent post-operative pneumonia in patients who are undergoing esophagectomy.
Authors: Yuki Sakamoto; Arisa Tanabe; Makiko Moriyama; Yoshihiko Otsuka; Madoka Funahara; Sakiko Soutome; Masahiro Umeda; Yuka Kojima Journal: Int J Environ Res Public Health Date: 2022-06-21 Impact factor: 4.614
Authors: Morad Chughtai; Chukwuweike U Gwam; Nequesha Mohamed; Anton Khlopas; Jared M Newman; Rafay Khan; Ali Nadhim; Shervin Shaffiy; Michael A Mont Journal: J Clin Med Res Date: 2017-04-26