Literature DB >> 27135075

Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.

Sameh Saad1, Naglaa Mohamed2, Amr Moghazy3, Gouda Ellabban3, Soliman El-Kamash3.   

Abstract

BACKGROUND: The trauma and injury severity score (TRISS) and Acute Physiology and Chronic Health Evaluation IV (APACHE IV) are accurate but complex. This study aimed to compare venous glucose, levels of serum lactate, and base deficit in polytraumatized patients as simple parameters to predict the mortality in these patients versus (TRISS) and (APACHE IV).
METHODS: This was a comparative cross-sectional study of 282 patients with polytrauma presented to the Emergency Department (ED).
RESULTS: The best cut off value of TRISS probability of survival score for prediction of mortality among poly-traumatized patients was ≤90. APACHE IV demonstrated 67% sensitivity and 95% specificity at 95% CI at cut off point 99. The best cutoff value of Random Blood Sugar was >140 mg/dl, with 89% sensitivity, 49% specificity; base deficit was less than -5.6 with 64% sensitivity, 93% specificity; lactate was >2.6 mmol/L with 92%, sensitivity, 42% specificity.
CONCLUSION: Venous glucose, serum lactate and base deficit are easy and rapid biochemical predictors of mortality in patients with polytrauma. These predictors could be used as TRISS and APACHE IV in predicting mortality.

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Year:  2016        PMID: 27135075     DOI: 10.5505/tjtes.2015.96832

Source DB:  PubMed          Journal:  Ulus Travma Acil Cerrahi Derg


  6 in total

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2.  Serum Lactate Level in Early Stage Is Associated With Acute Kidney Injury in Traumatic Brain Injury Patients.

Authors:  Ruoran Wang; Shaobo Wang; Jing Zhang; Min He; Jianguo Xu
Journal:  Front Surg       Date:  2022-01-31

3.  Systemic Infection Predictive Value of Procalcitonin to Lactic Acid Ratio in Diabetes Ketoacidosis Patients.

Authors:  Bin Huang; Shengju Yang; Shandong Ye
Journal:  Diabetes Metab Syndr Obes       Date:  2022-07-22       Impact factor: 3.249

4.  The Association Between Serum Lactate Concentration, Base Deficit, and Mortality in Polytrauma Patients as a Prognostic Factor: An Observational Study.

Authors:  Divya Jyoti; Anil Kumar; Talat Halim; Ahmed A Hai
Journal:  Cureus       Date:  2022-08-20

5.  Comparison of base excess, lactate and pH predicting 72-h mortality of multiple trauma.

Authors:  Junfang Qi; Long Bao; Peng Yang; Du Chen
Journal:  BMC Emerg Med       Date:  2021-07-07

6.  A Clinical Study on the Initial Assessment of Arterial Lactate and Base Deficit as Predictors of Outcome in Trauma Patients.

Authors:  Rameshbabu Homanna Javali; Prithvishree Ravindra; Akkamahadevi Patil; Madhu Srinivasarangan; Harshit Mundada; S B Adarsh; S Nisarg
Journal:  Indian J Crit Care Med       Date:  2017-11
  6 in total

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