Literature DB >> 27134967

Multifocal Tumefactive Demyelination Mimicking Intracranial Neoplasm.

Tom George1, Soumya Cicilet2, Ravi Hoisala3, Prithilata Rout4.   

Abstract

Demyelinating disease presenting with clinical and radiologic features similar to a brain tumour is referred to as tumefactive demyelination. These lesions pose considerable diagnostic uncertainty. This is partly due to the atypical neurologic symptoms that the patient can present with as a consequence of the size, location, and potential for associated mass effect and oedema. The MRI appearance of these lesions can aid in preoperative diagnosis and assist with the final pathologic interpretation. We report a case of tumefactive demyelination where MRI played a vital role in arriving at a diagnosis. The diagnosis was confirmed histopathologically.

Entities:  

Keywords:  Differential diagnosis; MRI; Ring enhancing

Year:  2016        PMID: 27134967      PMCID: PMC4843352          DOI: 10.7860/JCDR/2016/15589.7465

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

Review 1.  The MRI appearance of tumefactive demyelinating lesions.

Authors:  Curtis A Given; B Scott Stevens; Charles Lee
Journal:  AJR Am J Roentgenol       Date:  2004-01       Impact factor: 3.959

Review 2.  Tumefactive demyelinating lesions.

Authors:  A P Dagher; J Smirniotopoulos
Journal:  Neuroradiology       Date:  1996-08       Impact factor: 2.804

3.  Variant of multiple sclerosis with dementia and tumefactive demyelinating brain lesions.

Authors:  Sherifa A Hamed
Journal:  World J Clin Cases       Date:  2015-06-16       Impact factor: 1.337

Review 4.  Multiple sclerosis and brain tumor: a diagnostic challenge.

Authors:  R J Paley; J A Persing; A Doctor; J J Westwater; J P Roberson; R F Edlich
Journal:  J Emerg Med       Date:  1989 May-Jun       Impact factor: 1.484

5.  Large focal tumor-like demyelinating lesions of the brain: intermediate entity between multiple sclerosis and acute disseminated encephalomyelitis? A study of 31 patients.

Authors:  J J Kepes
Journal:  Ann Neurol       Date:  1993-01       Impact factor: 10.422

6.  Primary Sjögren Syndrome with tumefactive central nervous system involvement.

Authors:  J Sanahuja; S Ordoñez-Palau; R Begué; L Brieva; D Boquet
Journal:  AJNR Am J Neuroradiol       Date:  2008-09-10       Impact factor: 3.825

7.  Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis.

Authors:  D J A Butteriss; A Ismail; D W Ellison; D Birchall
Journal:  Br J Radiol       Date:  2003-09       Impact factor: 3.039

8.  The open ring. A new imaging sign in demyelinating disease.

Authors:  J C Masdeu; J Moreira; S Trasi; P Visintainer; R Cavaliere; M Grundman
Journal:  J Neuroimaging       Date:  1996-04       Impact factor: 2.486

9.  Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis.

Authors:  C F Lucchinetti; R H Gavrilova; I Metz; J E Parisi; B W Scheithauer; S Weigand; K Thomsen; J Mandrekar; A Altintas; B J Erickson; F König; C Giannini; H Lassmann; L Linbo; S J Pittock; W Brück
Journal:  Brain       Date:  2008-06-05       Impact factor: 13.501

  9 in total
  1 in total

1.  Progression of tumefactive demyelinating lesion in a child demonstrated with MRI.

Authors:  Marta De Simone; Barbara Brogna; Daniele Litterio Spitaleri; Giulio Cicarelli; Roberta Fantozzi; Bruno Guida
Journal:  Radiol Case Rep       Date:  2017-12-08
  1 in total

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