Literature DB >> 27134552

Polymer - Nanoparticle Assemblies for Array Based Sensing.

Brian Creran1, Uwe H F Bunz2, Vincent M Rotello1.   

Abstract

Sensing clinically relevant biomolecules is crucial for the detection and prevention of disease. Currently used detection methods tend to be expensive, time intensive, and specific for only one particular biomolecule of interest. Nanoparticle-based arrays using conjugated polymers have emerged as an analytical and potential clinical tool, allowing detection of a wide range of biomolecules using selective, not specific, sensor components. In this report, we highlight recent progress in nanoparticle - polymer sensor arrays in both the fundamental understanding of how the sensor arrays function as well as the detection of clinically relevant bacteria and cells.

Entities:  

Keywords:  Biosensing; conjugated polymers; displacement assay; nanoparticles

Year:  2015        PMID: 27134552      PMCID: PMC4845962          DOI: 10.2174/1385272819666150318221301

Source DB:  PubMed          Journal:  Curr Org Chem        ISSN: 1385-2728            Impact factor:   2.180


  33 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-23       Impact factor: 11.205

10.  Detection and differentiation of normal, cancerous, and metastatic cells using nanoparticle-polymer sensor arrays.

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1.  Cyclodextrin-Promoted Fluorescence Detection of Aromatic Toxicants and Toxicant Metabolites in Commercial Milk Products.

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