Elsa Iannicelli1, Isabella Martini2, Claudia Fantini3, Claudio Papi4, Paola Gigante5, Francesco Carbonetti6, Marco Di Pietropaolo7, Vincenzo David8. 1. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: elsa.iannicelli@uniroma1.it. 2. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: isabella.martini88@gmail.com. 3. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: fantiniclaudia@libero.it. 4. Gastroenterology Unit, San Filippo Neri Hospital, Via Martinotti 20, 00100, Rome, Italy. Electronic address: c.papi09@gmail.it. 5. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: pgigante@live.it. 6. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: francescocarbonetti799@gmail.com. 7. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: marco.dp8@gmail.com. 8. Radiology Unit, "Sapienza" University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035, 00189, Rome, Italy. Electronic address: enzodavid46@gmail.com.
Abstract
PURPOSE: The aim is to determine the accuracy of magnetic resonance enterography (MRE) in evaluating Crohn's disease (CD) activity. MATERIALS AND METHODS: Seventy-seven patients with CD underwent MRE. The primary analysis was to determine associations between MRE findings, Harvey-Bradshaw Index, and C-reactive protein (CRP), then we have created a new MRE score that it was also correlated with clinical and laboratory data. RESULTS: MRE score for CD significantly correlates with CRP (P=.003). Significant associations were found between degree of contrast enhancement and CRP (P=.002) and between comb sign and CRP (P=.001). CONCLUSIONS: These results make MRE an important instrument for evaluation of CD activity.
PURPOSE: The aim is to determine the accuracy of magnetic resonance enterography (MRE) in evaluating Crohn's disease (CD) activity. MATERIALS AND METHODS: Seventy-seven patients with CD underwent MRE. The primary analysis was to determine associations between MRE findings, Harvey-Bradshaw Index, and C-reactive protein (CRP), then we have created a new MRE score that it was also correlated with clinical and laboratory data. RESULTS: MRE score for CD significantly correlates with CRP (P=.003). Significant associations were found between degree of contrast enhancement and CRP (P=.002) and between comb sign and CRP (P=.001). CONCLUSIONS: These results make MRE an important instrument for evaluation of CD activity.