Karim Samji1, Abdulmohsen Alrashed1, Wael M Shabana1, Matthew Df McInnes1, Ersin Bayram2, Nicola Schieda3. 1. Department of Diagnostic Imaging, The Ottawa Hospital, 1053 Carling Avenue, Ottawa, ON, Canada K1Y 4E9. 2. Global MR Applications and Workflow, GE Healthcare, Houston, TX, USA. 3. Department of Diagnostic Imaging, The Ottawa Hospital, 1053 Carling Avenue, Ottawa, ON, Canada K1Y 4E9. Electronic address: nschieda@toh.on.ca.
Abstract
PURPOSE: To compare T1-weighted (T1W) fast spin echo (FSE) to T1W 3-dimensional gradient recalled echo (LAVA) with fat water separation (FLEX) in prostate cancer (PCa). METHODOLOGY: With institutional review board waiver, 39 patients underwent 3-T magnetic resonance imaging including T1W LAVA FLEX (157s)/T1W FSE (316s). Two radiologists assessed (a) image quality/sharpness, (b) presence/severity of artifacts, and (c) skeletal (N=22)/nodal (N=9) metastases. Results were compared using Wilcoxon signed-rank test/receiver operator characteristic analysis. RESULTS: With T1W LAVA FLEX, image quality/sharpness improved (P<.001) with less motion (P=.002-.03) and no difference in phase-encoding artifact (P>.05). One patient had moderate fat/water swap. Detection of skeletal metastases was unchanged (P>.05) and nodal metastases either improved (P=.002) or were comparable (P=.16) using T1W LAVA FLEX. CONCLUSION: T1W LAVA FLEX improves image quality, lessens motion artifact, and is comparable or improves detection of metastases in PCa with reduction in acquisition time.
PURPOSE: To compare T1-weighted (T1W) fast spin echo (FSE) to T1W 3-dimensional gradient recalled echo (LAVA) with fat water separation (FLEX) in prostate cancer (PCa). METHODOLOGY: With institutional review board waiver, 39 patients underwent 3-T magnetic resonance imaging including T1W LAVA FLEX (157s)/T1W FSE (316s). Two radiologists assessed (a) image quality/sharpness, (b) presence/severity of artifacts, and (c) skeletal (N=22)/nodal (N=9) metastases. Results were compared using Wilcoxon signed-rank test/receiver operator characteristic analysis. RESULTS: With T1W LAVA FLEX, image quality/sharpness improved (P<.001) with less motion (P=.002-.03) and no difference in phase-encoding artifact (P>.05). One patient had moderate fat/water swap. Detection of skeletal metastases was unchanged (P>.05) and nodal metastases either improved (P=.002) or were comparable (P=.16) using T1W LAVA FLEX. CONCLUSION: T1W LAVA FLEX improves image quality, lessens motion artifact, and is comparable or improves detection of metastases in PCa with reduction in acquisition time.