Rajesh Kumar Goit1, Abdul Haque Ansari2. 1. Department of Physiology, Nepalgunj Medical College, Banke, Nepal. Electronic address: goit_rajesh@yahoo.com. 2. Department of Physiology, Birat Medical College, Biratnagar, Nepal. Electronic address: ansari782000@yahoo.com.
Abstract
AIM: The aim of the study was to compare heart rate variability (HRV) of newly diagnosed essential hypertensive subjects with controls. METHODS: The study was conducted on 120 hypertensive subjects and 120 controls. RESULTS: The time-domain measures, standard deviation of all RR intervals (SDNN), the square root of the mean of the sum of the squares of differences between adjacent RR intervals (RMSSD), and percentage of consecutive RR intervals that differ by more than 50ms (pNN50) which reflect parasympathetic activity were significantly less in hypertensive subjects. In frequency-domain measures, high frequency [HF (ms(2))] and [HF (nu)], which reflects parasympathetic activity, was significantly less in hypertensive subjects while LF (nu) and LF/HF (%), which reflect sympathetic activity, were comparable between the groups. CONCLUSION: These findings suggest that HRV is reduced in subjects with newly diagnosed essential hypertension and the parasympathetic dysregulation is present in the early stage of essential hypertension.
AIM: The aim of the study was to compare heart rate variability (HRV) of newly diagnosed essential hypertensive subjects with controls. METHODS: The study was conducted on 120 hypertensive subjects and 120 controls. RESULTS: The time-domain measures, standard deviation of all RR intervals (SDNN), the square root of the mean of the sum of the squares of differences between adjacent RR intervals (RMSSD), and percentage of consecutive RR intervals that differ by more than 50ms (pNN50) which reflect parasympathetic activity were significantly less in hypertensive subjects. In frequency-domain measures, high frequency [HF (ms(2))] and [HF (nu)], which reflects parasympathetic activity, was significantly less in hypertensive subjects while LF (nu) and LF/HF (%), which reflect sympathetic activity, were comparable between the groups. CONCLUSION: These findings suggest that HRV is reduced in subjects with newly diagnosed essential hypertension and the parasympathetic dysregulation is present in the early stage of essential hypertension.
Authors: Jimena Rodríguez-Carbó; José M Torres-Arellano; Nydia Ávila-Vanzzini; Rashidi Springall; Rafael Bojalil; Oscar Infante; Claudia Lerma; Juan Carlos Echeverría Journal: J Clin Med Date: 2022-08-16 Impact factor: 4.964
Authors: Ilja M Nolte; M Loretto Munoz; Vinicius Tragante; Azmeraw T Amare; Rick Jansen; Ahmad Vaez; Benedikt von der Heyde; Christy L Avery; Joshua C Bis; Bram Dierckx; Jenny van Dongen; Stephanie M Gogarten; Philippe Goyette; Jussi Hernesniemi; Ville Huikari; Shih-Jen Hwang; Deepali Jaju; Kathleen F Kerr; Alexander Kluttig; Bouwe P Krijthe; Jitender Kumar; Sander W van der Laan; Leo-Pekka Lyytikäinen; Adam X Maihofer; Arpi Minassian; Peter J van der Most; Martina Müller-Nurasyid; Michel Nivard; Erika Salvi; James D Stewart; Julian F Thayer; Niek Verweij; Andrew Wong; Delilah Zabaneh; Mohammad H Zafarmand; Abdel Abdellaoui; Sulayma Albarwani; Christine Albert; Alvaro Alonso; Foram Ashar; Juha Auvinen; Tomas Axelsson; Dewleen G Baker; Paul I W de Bakker; Matteo Barcella; Riad Bayoumi; Rob J Bieringa; Dorret Boomsma; Gabrielle Boucher; Annie R Britton; Ingrid Christophersen; Andrea Dietrich; George B Ehret; Patrick T Ellinor; Markku Eskola; Janine F Felix; John S Floras; Oscar H Franco; Peter Friberg; Maaike G J Gademan; Mark A Geyer; Vilmantas Giedraitis; Catharina A Hartman; Daiane Hemerich; Albert Hofman; Jouke-Jan Hottenga; Heikki Huikuri; Nina Hutri-Kähönen; Xavier Jouven; Juhani Junttila; Markus Juonala; Antti M Kiviniemi; Jan A Kors; Meena Kumari; Tatiana Kuznetsova; Cathy C Laurie; Joop D Lefrandt; Yong Li; Yun Li; Duanping Liao; Marian C Limacher; Henry J Lin; Cecilia M Lindgren; Steven A Lubitz; Anubha Mahajan; Barbara McKnight; Henriette Meyer Zu Schwabedissen; Yuri Milaneschi; Nina Mononen; Andrew P Morris; Mike A Nalls; Gerjan Navis; Melanie Neijts; Kjell Nikus; Kari E North; Daniel T O'Connor; Johan Ormel; Siegfried Perz; Annette Peters; Bruce M Psaty; Olli T Raitakari; Victoria B Risbrough; Moritz F Sinner; David Siscovick; Johannes H Smit; Nicholas L Smith; Elsayed Z Soliman; Nona Sotoodehnia; Jan A Staessen; Phyllis K Stein; Adrienne M Stilp; Katarzyna Stolarz-Skrzypek; Konstantin Strauch; Johan Sundström; Cees A Swenne; Ann-Christine Syvänen; Jean-Claude Tardif; Kent D Taylor; Alexander Teumer; Timothy A Thornton; Lesley E Tinker; André G Uitterlinden; Jessica van Setten; Andreas Voss; Melanie Waldenberger; Kirk C Wilhelmsen; Gonneke Willemsen; Quenna Wong; Zhu-Ming Zhang; Alan B Zonderman; Daniele Cusi; Michele K Evans; Halina K Greiser; Pim van der Harst; Mohammad Hassan; Erik Ingelsson; Marjo-Riitta Järvelin; Stefan Kääb; Mika Kähönen; Mika Kivimaki; Charles Kooperberg; Diana Kuh; Terho Lehtimäki; Lars Lind; Caroline M Nievergelt; Chris J O'Donnell; Albertine J Oldehinkel; Brenda Penninx; Alexander P Reiner; Harriëtte Riese; Arie M van Roon; John D Rioux; Jerome I Rotter; Tamar Sofer; Bruno H Stricker; Henning Tiemeier; Tanja G M Vrijkotte; Folkert W Asselbergs; Bianca J J M Brundel; Susan R Heckbert; Eric A Whitsel; Marcel den Hoed; Harold Snieder; Eco J C de Geus Journal: Nat Commun Date: 2017-06-14 Impact factor: 17.694