Merve Erkmen Almaz1, Işıl Şaroğlu Sönmez2, Zeynep Ökte3, Aylin Akbay Oba4. 1. Department of Pediatric Dentistry, Faculty of Dentistry, Kırıkkale University, Kırıkkale, Turkey. dt.merveerkmen@gmail.com. 2. Department of Pediatric Dentistry, Faculty of Dentistry, Adnan Menderes University, Aydın, Turkey. 3. Department of Pediatric Dentistry, Faculty of Dentistry, Ankara University, Ankara, Turkey. 4. Department of Pediatric Dentistry, Faculty of Dentistry, Kırıkkale University, Kırıkkale, Turkey.
Abstract
OBJECTIVE: The aim of our study was to evaluate the efficacy of an herbal lollipop containing licorice root extract on salivary Streptococcus mutans in caries-free and high-caries-risk children. MATERIALS AND METHODS: The study was conducted in caries-free and high-caries-risk children, aged 5-11 years (n = 108). The groups were caries-free children (group A); high-caries-risk children whose dental treatment was completed before lollipop use (group B); and high-caries-risk children who did not comply with dental treatment (group C). The groups were divided into two subgroups: herbal (A-1, B-1, C-1) and placebo lollipops (A-2, B-2, C-2). Saliva samples were taken before dental treatment, before and after consuming lollipops, and at 3 months after consuming lollipops. The results were statistically analyzed with chi-squared test. RESULTS: Only in group C-1 (high-risk, using herbal lollipops) that significant reduction was observed in salivary S. mutans levels after lollipop use (p = 0.033), and only in the same group (C-1), there was significant difference between after lollipop use and third month levels (p = 0.006). CONCLUSIONS: Herbal lollipops could be recommended to children with high-caries risk who do not comply with dental treatment in place of high-carbohydrate snacks. CLINICAL RELEVANCE: The paper provides a perspective on using herbal products in high-risk children for reducing salivary S. mutans counts.
RCT Entities:
OBJECTIVE: The aim of our study was to evaluate the efficacy of an herbal lollipop containing licorice root extract on salivary Streptococcus mutans in caries-free and high-caries-risk children. MATERIALS AND METHODS: The study was conducted in caries-free and high-caries-risk children, aged 5-11 years (n = 108). The groups were caries-free children (group A); high-caries-risk children whose dental treatment was completed before lollipop use (group B); and high-caries-risk children who did not comply with dental treatment (group C). The groups were divided into two subgroups: herbal (A-1, B-1, C-1) and placebo lollipops (A-2, B-2, C-2). Saliva samples were taken before dental treatment, before and after consuming lollipops, and at 3 months after consuming lollipops. The results were statistically analyzed with chi-squared test. RESULTS: Only in group C-1 (high-risk, using herbal lollipops) that significant reduction was observed in salivary S. mutans levels after lollipop use (p = 0.033), and only in the same group (C-1), there was significant difference between after lollipop use and third month levels (p = 0.006). CONCLUSIONS: Herbal lollipops could be recommended to children with high-caries risk who do not comply with dental treatment in place of high-carbohydrate snacks. CLINICAL RELEVANCE: The paper provides a perspective on using herbal products in high-risk children for reducing salivary S. mutans counts.
Authors: Stefan Gafner; Chantal Bergeron; Jacquelyn R Villinski; Markus Godejohann; Pavel Kessler; John H Cardellina; Daneel Ferreira; Karine Feghali; Daniel Grenier Journal: J Nat Prod Date: 2011-11-10 Impact factor: 4.050
Authors: Mônica Fernandes Gomes; Luigi Giovanni Bernardo Sichi; Lilian Chrystiane Giannasi; José Benedito Oliveira Amorim; João Carlos da Rocha; Cristiane Yumi Koga-Ito; Miguel Angel Castillo Salgado Journal: Case Rep Dent Date: 2018-03-20