Wei Liu1, Chen Huang2, Yu Hu3, Qingyan Fu4, Zhijun Zou1, Chanjuan Sun1, Li Shen5, Xueying Wang1, Jiao Cai1, Jun Pan4, Yanmin Huang4, Jing Chang6, Yuexia Sun7, Jan Sundell8. 1. Department of Building Environment and Energy Engineering, School of Environment and Architecture, University of Shanghai for Science and Technology (USST), Shanghai, China. 2. Department of Building Environment and Energy Engineering, School of Environment and Architecture, University of Shanghai for Science and Technology (USST), Shanghai, China. Electronic address: hcyhyywj@163.com. 3. Tongji Architectural Design (Group) Company Limited (TJAD), Shanghai, China. 4. Shanghai Environmental Monitoring Center (SEMC), Shanghai, China. 5. R&B Technology (Shanghai) Company Limited, Shanghai, China. 6. Department of Building Environment and Energy Engineering, School of Environment and Architecture, University of Shanghai for Science and Technology (USST), Shanghai, China; Department of Thermal Energy and Power Engineering, Shandong Jiaotong University, Jinan, China. 7. School of Environmental Science and Engineering, Tianjin University, Tianjin, China. 8. Department of Building Environment and Energy Engineering, School of Environment and Architecture, University of Shanghai for Science and Technology (USST), Shanghai, China; Department of Building Science, Tsinghua University, Beijing, China.
Abstract
BACKGROUND: Associations of ambient air pollutants with respiratory health are inconsistent. OBJECTIVES: We analyzed the associations of gestational and early life exposures to air pollutants with doctor-diagnosed asthma, allergic rhinitis, and pneumonia in children. METHODS: We selected 3358 preschool children who did not alter residences after birth from a cross-sectional study in 2011-2012 in Shanghai, China. Parents reported children's respiratory health history, home environment, and family lifestyle behaviors. We collected daily concentrations of sulphur dioxide (SO2), nitrogen dioxide (NO2), and particulate matter with an aerodynamic diameter ≤10μm (PM10) during the child's total lifetime (2006-2012) for each district where the children lived. We analyzed the associations using logistic regression models. RESULTS: After adjusting for covariates and the other studied pollutants, we found that exposure to NO2 (increment of 20μg/m(3)) during the first year of life was significantly associated with asthma [odds ratio (OR)=1.77; 95% confidence interval (CI): 1.29-2.43] and allergic rhinitis (OR=1.67; 95% CI: 1.07-2.61). Exposure to NO2 during gestation, the first two and three years, and over total lifetimewas all consistently associated with increased odds of allergic rhinitis. Quartiles of NO2 concentration during different exposure periods showed a slight dose-response relationship with the studied diseases. These diseases had significant associations with pollutant mixtures that included NO2, but had no significant association with exposures to SO2 and PM10 individually or in mixtures. CONCLUSIONS: Gestational and early life exposures to ambient NO2 are risk factors for childhood respiratory diseases.
BACKGROUND: Associations of ambient air pollutants with respiratory health are inconsistent. OBJECTIVES: We analyzed the associations of gestational and early life exposures to air pollutants with doctor-diagnosed asthma, allergic rhinitis, and pneumonia in children. METHODS: We selected 3358 preschool children who did not alter residences after birth from a cross-sectional study in 2011-2012 in Shanghai, China. Parents reported children's respiratory health history, home environment, and family lifestyle behaviors. We collected daily concentrations of sulphur dioxide (SO2), nitrogen dioxide (NO2), and particulate matter with an aerodynamic diameter ≤10μm (PM10) during the child's total lifetime (2006-2012) for each district where the children lived. We analyzed the associations using logistic regression models. RESULTS: After adjusting for covariates and the other studied pollutants, we found that exposure to NO2 (increment of 20μg/m(3)) during the first year of life was significantly associated with asthma [odds ratio (OR)=1.77; 95% confidence interval (CI): 1.29-2.43] and allergic rhinitis (OR=1.67; 95% CI: 1.07-2.61). Exposure to NO2 during gestation, the first two and three years, and over total lifetimewas all consistently associated with increased odds of allergic rhinitis. Quartiles of NO2 concentration during different exposure periods showed a slight dose-response relationship with the studied diseases. These diseases had significant associations with pollutant mixtures that included NO2, but had no significant association with exposures to SO2 and PM10 individually or in mixtures. CONCLUSIONS: Gestational and early life exposures to ambient NO2 are risk factors for childhood respiratory diseases.
Authors: Miaomiao Liu; Yining Huang; Zongwei Ma; Zhou Jin; Xingyu Liu; Haikun Wang; Yang Liu; Jinnan Wang; Matti Jantunen; Jun Bi; Patrick L Kinney Journal: Environ Int Date: 2016-10-13 Impact factor: 9.621
Authors: Nadya Y Rivera Rivera; Marcela Tamayo-Ortiz; Adriana Mercado García; Allan C Just; Itai Kloog; Martha Maria Téllez-Rojo; Robert O Wright; Rosalind J Wright; Maria José Rosa Journal: Environ Res Date: 2020-10-22 Impact factor: 6.498
Authors: Éric Lavigne; Marc-André Bélair; Daniel Rodriguez Duque; Minh T Do; David M Stieb; Perry Hystad; Aaron van Donkelaar; Randall V Martin; Daniel L Crouse; Eric Crighton; Hong Chen; Richard T Burnett; Scott Weichenthal; Paul J Villeneuve; Teresa To; Jeffrey R Brook; Markey Johnson; Sabit Cakmak; Abdool S Yasseen; Mark Walker Journal: Eur Respir J Date: 2018-02-01 Impact factor: 16.671