Literature DB >> 27127757

Toward precision medicine in neurological diseases.

Lin Tan1, Teng Jiang1, Lan Tan1, Jin-Tai Yu1.   

Abstract

Technological development has paved the way for accelerated genomic discovery and is bringing precision medicine into view. The goal of precision medicine is to deliver optimally targeted and timed interventions tailored to an individual's molecular drivers of disease. Neurological diseases are promisingly suited models for precision medicine because of the rapidly expanding genetic knowledge base, phenotypic classification, the development of biomarkers and the potential modifying treatments. Moving forward, it is crucial that through these integrated research platforms to provide analysis both for accurate personal genome analysis and gene and drug discovery. Here we describe our vision of how precision medicine can bring greater clarity to the clinical and biological complexity of neurological diseases.

Entities:  

Keywords:  Precision medicine; disease; genetics; neurology

Year:  2016        PMID: 27127757      PMCID: PMC4828730          DOI: 10.21037/atm.2016.03.26

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  42 in total

Review 1.  Novel disease-modifying therapies for Alzheimer's disease.

Authors:  Teng Jiang; Jin-Tai Yu; Lan Tan
Journal:  J Alzheimers Dis       Date:  2012       Impact factor: 4.472

Review 2.  Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective.

Authors:  Rudolph E Tanzi; Lars Bertram
Journal:  Cell       Date:  2005-02-25       Impact factor: 41.582

3.  Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

Authors:  Lucia A Hindorff; Praveen Sethupathy; Heather A Junkins; Erin M Ramos; Jayashri P Mehta; Francis S Collins; Teri A Manolio
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-27       Impact factor: 11.205

4.  Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.

Authors:  Bruno Dubois; Howard H Feldman; Claudia Jacova; Harald Hampel; José Luis Molinuevo; Kaj Blennow; Steven T DeKosky; Serge Gauthier; Dennis Selkoe; Randall Bateman; Stefano Cappa; Sebastian Crutch; Sebastiaan Engelborghs; Giovanni B Frisoni; Nick C Fox; Douglas Galasko; Marie-Odile Habert; Gregory A Jicha; Agneta Nordberg; Florence Pasquier; Gil Rabinovici; Philippe Robert; Christopher Rowe; Stephen Salloway; Marie Sarazin; Stéphane Epelbaum; Leonardo C de Souza; Bruno Vellas; Pieter J Visser; Lon Schneider; Yaakov Stern; Philip Scheltens; Jeffrey L Cummings
Journal:  Lancet Neurol       Date:  2014-06       Impact factor: 44.182

Review 5.  Novel Diagnostic and Monitoring Tools in Stroke: an Individualized Patient-Centered Precision Medicine Approach.

Authors:  Sulette de Villiers; Albe Swanepoel; Janette Bester; Etheresia Pretorius
Journal:  J Atheroscler Thromb       Date:  2015-12-19       Impact factor: 4.928

6.  Genome-wide serum microRNA expression profiling identifies serum biomarkers for Alzheimer's disease.

Authors:  Lin Tan; Jin-Tai Yu; Meng-Shan Tan; Qiu-Yan Liu; Hui-Fu Wang; Wei Zhang; Teng Jiang; Lan Tan
Journal:  J Alzheimers Dis       Date:  2014       Impact factor: 4.472

7.  Image-based modeling and precision medicine: patient-specific carotid and coronary plaque assessment and predictions.

Authors:  Dalin Tang; Chun Yang; Jie Zheng; Gador Canton; Richard G Bach; Thomas S Hatsukami; Liang Wang; Deshan Yang; Kristen L Billiar; Chun Yuan
Journal:  IEEE Trans Biomed Eng       Date:  2013-01-25       Impact factor: 4.538

8.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Authors:  Adam C Naj; Gyungah Jun; Gary W Beecham; Li-San Wang; Badri Narayan Vardarajan; Jacqueline Buros; Paul J Gallins; Joseph D Buxbaum; Gail P Jarvik; Paul K Crane; Eric B Larson; Thomas D Bird; Bradley F Boeve; Neill R Graff-Radford; Philip L De Jager; Denis Evans; Julie A Schneider; Minerva M Carrasquillo; Nilufer Ertekin-Taner; Steven G Younkin; Carlos Cruchaga; John S K Kauwe; Petra Nowotny; Patricia Kramer; John Hardy; Matthew J Huentelman; Amanda J Myers; Michael M Barmada; F Yesim Demirci; Clinton T Baldwin; Robert C Green; Ekaterina Rogaeva; Peter St George-Hyslop; Steven E Arnold; Robert Barber; Thomas Beach; Eileen H Bigio; James D Bowen; Adam Boxer; James R Burke; Nigel J Cairns; Chris S Carlson; Regina M Carney; Steven L Carroll; Helena C Chui; David G Clark; Jason Corneveaux; Carl W Cotman; Jeffrey L Cummings; Charles DeCarli; Steven T DeKosky; Ramon Diaz-Arrastia; Malcolm Dick; Dennis W Dickson; William G Ellis; Kelley M Faber; Kenneth B Fallon; Martin R Farlow; Steven Ferris; Matthew P Frosch; Douglas R Galasko; Mary Ganguli; Marla Gearing; Daniel H Geschwind; Bernardino Ghetti; John R Gilbert; Sid Gilman; Bruno Giordani; Jonathan D Glass; John H Growdon; Ronald L Hamilton; Lindy E Harrell; Elizabeth Head; Lawrence S Honig; Christine M Hulette; Bradley T Hyman; Gregory A Jicha; Lee-Way Jin; Nancy Johnson; Jason Karlawish; Anna Karydas; Jeffrey A Kaye; Ronald Kim; Edward H Koo; Neil W Kowall; James J Lah; Allan I Levey; Andrew P Lieberman; Oscar L Lopez; Wendy J Mack; Daniel C Marson; Frank Martiniuk; Deborah C Mash; Eliezer Masliah; Wayne C McCormick; Susan M McCurry; Andrew N McDavid; Ann C McKee; Marsel Mesulam; Bruce L Miller; Carol A Miller; Joshua W Miller; Joseph E Parisi; Daniel P Perl; Elaine Peskind; Ronald C Petersen; Wayne W Poon; Joseph F Quinn; Ruchita A Rajbhandary; Murray Raskind; Barry Reisberg; John M Ringman; Erik D Roberson; Roger N Rosenberg; Mary Sano; Lon S Schneider; William Seeley; Michael L Shelanski; Michael A Slifer; Charles D Smith; Joshua A Sonnen; Salvatore Spina; Robert A Stern; Rudolph E Tanzi; John Q Trojanowski; Juan C Troncoso; Vivianna M Van Deerlin; Harry V Vinters; Jean Paul Vonsattel; Sandra Weintraub; Kathleen A Welsh-Bohmer; Jennifer Williamson; Randall L Woltjer; Laura B Cantwell; Beth A Dombroski; Duane Beekly; Kathryn L Lunetta; Eden R Martin; M Ilyas Kamboh; Andrew J Saykin; Eric M Reiman; David A Bennett; John C Morris; Thomas J Montine; Alison M Goate; Deborah Blacker; Debby W Tsuang; Hakon Hakonarson; Walter A Kukull; Tatiana M Foroud; Jonathan L Haines; Richard Mayeux; Margaret A Pericak-Vance; Lindsay A Farrer; Gerard D Schellenberg
Journal:  Nat Genet       Date:  2011-04-03       Impact factor: 38.330

Review 9.  Developing precision stroke imaging.

Authors:  Edward Feldmann; David S Liebeskind
Journal:  Front Neurol       Date:  2014-03-24       Impact factor: 4.003

Review 10.  Lessons of ALS imaging: Pitfalls and future directions - A critical review.

Authors:  Peter Bede; Orla Hardiman
Journal:  Neuroimage Clin       Date:  2014-02-27       Impact factor: 4.881

View more
  8 in total

1.  PRECISION MEDICINE - The Golden Gate for Detection, Treatment and Prevention of Alzheimer's Disease.

Authors:  H Hampel; S E O'Bryant; J I Castrillo; C Ritchie; K Rojkova; K Broich; N Benda; R Nisticò; R A Frank; B Dubois; V Escott-Price; S Lista
Journal:  J Prev Alzheimers Dis       Date:  2016-09-06

Review 2.  The epileptic and nonepileptic spectrum of paroxysmal dyskinesias: Channelopathies, synaptopathies, and transportopathies.

Authors:  Roberto Erro; Kailash P Bhatia; Alberto J Espay; Pasquale Striano
Journal:  Mov Disord       Date:  2017-01-16       Impact factor: 10.338

3.  Commentary on ICH guideline on genomic sampling and data management-enabling opportunities in drug development and patient treatment.

Authors:  Falk Ehmann; Jeroen Aerssens; Rebecca Blanchard
Journal:  Br J Clin Pharmacol       Date:  2020-05-18       Impact factor: 4.335

Review 4.  Amyotrophic Lateral Sclerosis: Current Status in Diagnostic Biomarkers.

Authors:  Katerina Kadena; Panayiotis Vlamos
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622

5.  Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms.

Authors:  Mohammad Asif Emon; Ashley Heinson; Ping Wu; Daniel Domingo-Fernández; Meemansa Sood; Henri Vrooman; Jean-Christophe Corvol; Phil Scordis; Martin Hofmann-Apitius; Holger Fröhlich
Journal:  Sci Rep       Date:  2020-11-05       Impact factor: 4.379

Review 6.  Precision and Personalized Medicine: How Genomic Approach Improves the Management of Cardiovascular and Neurodegenerative Disease.

Authors:  Oriana Strianese; Francesca Rizzo; Michele Ciccarelli; Gennaro Galasso; Ylenia D'Agostino; Annamaria Salvati; Carmine Del Giudice; Paola Tesorio; Maria Rosaria Rusciano
Journal:  Genes (Basel)       Date:  2020-07-06       Impact factor: 4.096

7.  Biomedical informatics applications for precision management of neurodegenerative diseases.

Authors:  Justin B Miller; Guogen Shan; Joseph Lombardo; Gustavo Jimenez-Maggoria
Journal:  Alzheimers Dement (N Y)       Date:  2018-06-13

8.  Towards realizing the vision of precision medicine: AI based prediction of clinical drug response.

Authors:  Johann de Jong; Ioana Cutcutache; Matthew Page; Sami Elmoufti; Cynthia Dilley; Holger Fröhlich; Martin Armstrong
Journal:  Brain       Date:  2021-07-28       Impact factor: 13.501

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.