Literature DB >> 27127384

Congenital Triangular Alopecia: The 127(th) Case.

Vivek Kumar Dey1, Tanvi Singh Bhadoria1, Animesh Saxena1, Avtar Kishan Jaisinghani1, Anjali Y Patil1, Neha Dubey1.   

Abstract

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Year:  2016        PMID: 27127384      PMCID: PMC4830181          DOI: 10.4103/0974-7753.179399

Source DB:  PubMed          Journal:  Int J Trichology        ISSN: 0974-7753


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Sir, We read the review article “congenital triangular alopecia (CTA)” with great interest, which was published recently (Int J Trichol 2015;7:48-53).[1] We appreciate the authors for their efforts on extensive search and analysis of this rare and less known disorder. A total of 126 cases have been reported till January 2015 worldwide. All these cases have been compiled beautifully by the authors. As CTA is a rarely reported entity, it is important to report each and every case seen. In our extensive online search, we did not find any new case of CTA reported after January 2015; therefore, we are presenting here the 127th case of CTA which we came across a month back. A 19-year-old male presented with a single patch of hair loss located over the right frontotemporal region of the scalp first noticed at early childhood, which remained persistent since its appearance [Figure 1]. There was no history of trauma or any other associated disorder. Parents were nonconsanguineous, and no family members were similarly affected. On examination, the patch was triangular to the oval of approximately 6 cm × 3 cm in size on the right frontotemporal regions with apex toward the vertex. On dermoscopic view alopecic area contained almost a normal number of hairs, although virtually all were vellus and no single terminal hair was found within the patch. At the margins, there was a transition zone containing both vellus and terminal hair. Therefore, there was no clear-cut margin of alopecic patch. Systemic examination was absolutely normal. Histopathology could not be performed as the patient did not consent for the same. The patient had diagnosed as a case of alopecia areata previously and treated with topical steroids without any benefit. We prescribed him topical minoxidil 5% to apply twice daily as it has shown to improve hair growth on the patch of CTA.[2] Possibility of satisfactory cosmetic result with follicular unit transplantation was also discussed with the patient, as it may give long-term satisfactory and sustained result.[3]
Figure 1

Congenital triangular alopecia affecting right frontotemporal region of the scalp in a 19-year-old male

Congenital triangular alopecia affecting right frontotemporal region of the scalp in a 19-year-old male CTA usually manifests at 2–5 years of age, but may present at birth or develops in adulthood.[4] Usually presents unilaterally, rarely seen bilateral in 20% cases.[5] Actual incidence is not known probably because the lesions are benign and nonprogressive, therefore, less reported. Moreover, many cases are misdiagnosed and treated for alopecia areata. An analysis in 6200 patients revealed 7 with triangular alopecia.[6] Genetic basis of CTA is not yet clear. However, its association with phakomatosis pigmentovascularis may provide evidence that it may originate from loss of heterozygosity. A heterozygous individual could be phenotypically normal. It may be a predominant trait.[7] Several familial cases have been described, but the usual presentation is sporadic. Androgenetic alopecia and alopecia areata are important differentials. In fact, androgenetic alopecia makes the diagnosis challenging if presented in overlap with CTA. As there is no specific treatment for this rare condition, the main aim of this article is to register the 127th case of CTA and also to sensitize and enlighten other practitioners about this rare case to prevent inadvertent use of steroids in such cases.

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Conflicts of interest

There are no conflicts of interest.
  7 in total

1.  Temporal triangular alopecia acquired in adulthood.

Authors:  C A Trakimas; L C Sperling
Journal:  J Am Acad Dermatol       Date:  1999-05       Impact factor: 11.527

2.  Clinical and histologic findings in temporal triangular alopecia.

Authors:  C Trakimas; L C Sperling; H G Skelton; K J Smith; J L Buker
Journal:  J Am Acad Dermatol       Date:  1994-08       Impact factor: 11.527

3.  Successful treatment of temporal triangular alopecia with topical minoxidil.

Authors:  Chan-Yl Bang; Ji-Won Byun; Min-Ji Kang; Bo-Hee Yang; Hee-Jin Song; Jeonghyun Shin; Gwang Seong Choi
Journal:  Ann Dermatol       Date:  2013-08-13       Impact factor: 1.444

4.  Congenital triangular alopecia (Brauer nevus).

Authors:  M J García-Hernández; A Rodríguez-Pichardo; F Camacho
Journal:  Pediatr Dermatol       Date:  1995-12       Impact factor: 1.588

Review 5.  Congenital triangular alopecia may be categorized as a paradominant trait.

Authors:  Rudolf Happle
Journal:  Eur J Dermatol       Date:  2003 Jul-Aug       Impact factor: 3.328

Review 6.  Congenital Triangular Alopecia.

Authors:  Vincent Chum Yin Li; Paul Devakar Yesudian
Journal:  Int J Trichology       Date:  2015 Apr-Jun

7.  Bilateral Temporal Triangular Alopecia Associated with Phakomatosis Pigmentovascularis Type IV Successfully Treated with Follicular Unit Transplantation.

Authors:  Robin Unger; Mohammed A Alsufyani
Journal:  Case Rep Dermatol Med       Date:  2011-09-06
  7 in total
  1 in total

1.  Atypical Presentation of Congenital Triangular Alopecia: A Case Series in Italy.

Authors:  Michela Starace; Miriam Anna Carpanese; Diego Abbenante; Francesca Bruni; Bianca Maria Piraccini; Aurora Alessandrini
Journal:  Dermatol Pract Concept       Date:  2020-10-26
  1 in total

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