Literature DB >> 27122957

A Rare Cause of Pulmonary Embolism and Seizure in a Young Man: Antiphospholipid Syndrome.

Shu-Hsu Lu1, Yi-Chen Wang1, Yi-Shan Wu2, Shih-Chung Huang1, Chin-Sheng Lin3.   

Abstract

UNLABELLED: Pulmonary embolism (PE) is a complication of underlying vascular thrombosis. The causes of PE are multi-factorial, and patients with PE present with various symptoms. We herein have presented the case of a 21-year-old man who initially developed palpitation, dyspnea, and seizure. Computed tomography of the chest ultimately indicated PE, and antiphospholipid syndrome (APS) was diagnosed with clinical thrombosis events and series presence of antiphospholipid antibodies. APS commonly causes vascular thrombosis within the vascular tree; however, nonthrombotic manifestations, such as seizure, may also occur. Clinicians should be aware of such non-thrombotic manifestations of APS to avoid misdiagnosis and inappropriate management. KEY WORDS: Antiphospholipid syndromePulmonary embolismSeizure.

Entities:  

Year:  2016        PMID: 27122957      PMCID: PMC4816925          DOI: 10.6515/acs20150413a

Source DB:  PubMed          Journal:  Acta Cardiol Sin        ISSN: 1011-6842            Impact factor:   2.672


  10 in total

Review 1.  The antiphospholipid syndrome.

Authors:  Jerrold S Levine; D Ware Branch; Joyce Rauch
Journal:  N Engl J Med       Date:  2002-03-07       Impact factor: 91.245

Review 2.  Epidemiology of the antiphospholipid antibody syndrome.

Authors:  M Petri
Journal:  J Autoimmun       Date:  2000-09       Impact factor: 7.094

3.  Nonthrombotic manifestations of the antiphospholipid syndrome: away from thrombosis?

Authors:  Ronald A Asherson; Ricard Cervera; Daniel Shepshelovich; Yehuda Shoenfeld
Journal:  J Rheumatol       Date:  2006-06       Impact factor: 4.666

4.  Pulmonary embolism presenting as seizures.

Authors:  J E Marine; S Z Goldhaber
Journal:  Chest       Date:  1997-09       Impact factor: 9.410

5.  Anti-CNS antibodies in childhood neurologic diseases.

Authors:  A V Plioplys; A Greaves; W Yoshida
Journal:  Neuropediatrics       Date:  1989-05       Impact factor: 1.947

6.  Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes.

Authors:  J Chapman; M Cohen-Armon; Y Shoenfeld; A D Korczyn
Journal:  Lupus       Date:  1999       Impact factor: 2.911

7.  Cerebral blood flow and glucose metabolism in multi-infarct-dementia related to primary antiphospholipid antibody syndrome.

Authors:  R Hilker; A Thiel; C Geisen; J Rudolf
Journal:  Lupus       Date:  2000       Impact factor: 2.911

Review 8.  Central nervous system involvement in the antiphospholipid (Hughes) syndrome.

Authors:  G Sanna; M L Bertolaccini; M J Cuadrado; M A Khamashta; G R V Hughes
Journal:  Rheumatology (Oxford)       Date:  2003-02       Impact factor: 7.580

9.  Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II.

Authors:  Paul D Stein; Afzal Beemath; Fadi Matta; John G Weg; Roger D Yusen; Charles A Hales; Russell D Hull; Kenneth V Leeper; H Dirk Sostman; Victor F Tapson; John D Buckley; Alexander Gottschalk; Lawrence R Goodman; Thomas W Wakefied; Pamela K Woodard
Journal:  Am J Med       Date:  2007-10       Impact factor: 4.965

Review 10.  Managing pulmonary embolism from presentation to extended treatment.

Authors:  Alexander T Cohen; Mark Dobromirski; Meredith M P Gurwith
Journal:  Thromb Res       Date:  2013-10-14       Impact factor: 3.944

  10 in total
  1 in total

1.  Seizures as the first clinical manifestation of acute pulmonary embolism: an underestimate issue in neurocritical care.

Authors:  Marco Zuin; Gianluca Rigatelli; Giovanni Zuliani; Alessandro Adami; Pietro Zonzin; Loris Roncon
Journal:  Neurol Sci       Date:  2020-02-10       Impact factor: 3.307

  1 in total

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