Literature DB >> 2712286

Evaluation of uncertainties for parameters in binding studies: the sum-of-squares profile and Monte Carlo estimation.

H A Saroff1.   

Abstract

Methods for characterization and evaluation of uncertainties in the parameter values for binding experiments are presented. A sum-of-squares profile is defined and illustrated. Sum-of-squares profiles give a qualitative description of both the uncertainties and correlation of parameters. The Monte Carlo method is developed as an accurate means of evaluating uncertainties in parameter values for nonlinear models. Examples are given for both actual and synthetic data.

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Year:  1989        PMID： 2712286     DOI： 10.1016/0003-2697(89)90287-x

Source DB:  PubMed          Journal:  Anal Biochem        ISSN： 0003-2697            Impact factor:   3.365


  10 in total

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Authors:  Adedayo A Fodeke; Allen P Minton
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Authors:  R Buscaglia; R D Gray; J B Chaires
Journal:  Biopolymers       Date:  2013-12       Impact factor: 2.505

5.  Analysis of protein binding to receptor-doped lipid monolayers by Monte Carlo simulation.

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7.  Modeling complex equilibria in isothermal titration calorimetry experiments: thermodynamic parameters estimation for a three-binding-site model.

Authors:  Vu H Le; Robert Buscaglia; Jonathan B Chaires; Edwin A Lewis
Journal:  Anal Biochem       Date:  2012-12-19       Impact factor: 3.365

8.  Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection.

Authors:  Robert Buscaglia; M Clarke Miller; William L Dean; Robert D Gray; Andrew N Lane; John O Trent; Jonathan B Chaires
Journal:  Nucleic Acids Res       Date:  2013-06-26       Impact factor: 16.971

9.  The Bacterial DNA Binding Protein MatP Involved in Linking the Nucleoid Terminal Domain to the Divisome at Midcell Interacts with Lipid Membranes.

Authors:  Begoña Monterroso; Silvia Zorrilla; Marta Sobrinos-Sanguino; Miguel Ángel Robles-Ramos; Carlos Alfonso; Bill Söderström; Nils Y Meiresonne; Jolanda Verheul; Tanneke den Blaauwen; Germán Rivas
Journal:  mBio       Date:  2019-05-28       Impact factor: 7.867

10.  Nucleotide and receptor density modulate binding of bacterial division FtsZ protein to ZipA containing lipid-coated microbeads.

Authors:  Marta Sobrinos-Sanguino; Silvia Zorrilla; Begoña Monterroso; Allen P Minton; Germán Rivas
Journal:  Sci Rep       Date:  2017-10-20       Impact factor: 4.379
  10 in total

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