Literature DB >> 27122830

Role of Left Main Coronary Artery Stenosis on Intraoperative Conversion and Mortality in Off-Pump Coronary Artery Bypass.

Jeng-Wei Chen1, Cheng-Hsin Lin2, Ron-Bin Hsu2.   

Abstract

BACKGROUND: Intraoperative conversion is a major threat in off-pump coronary artery bypass (OPCAB). The conversion rate depends on patient selection and surgeon experience. Previous studies have demonstrated the feasibility of OPCAB for patients with left main coronary artery stenosis (LMCAS) ≥ 50%. However, no studies have focused on the role of LMCAS ≥ 90%. We sought to assess the impact of LMCAS ≥ 90% on the conversion rate and mortality in OPCAB.
METHODS: We conducted a retrospective review of 1055 consecutive unselected patients undergoing OPCAB between 2000 and 2012. The patients in our study were divided into 3 groups by the severity of LMCAS.
RESULTS: LMCAS was < 50% in 704, 50-90% in 266, and ≥ 90% in 85 patients. LMCAS was not associated with major postoperative complications and hospital mortality, although preoperative cardiogenic shock was present in 6.3%. Overall, the conversion rate was 10.1%:11.4% in LMCAS < 50%, 5.6% in LMCAS 50-90%, and 14.1% in LMCAS ≥ 90%. Operation status, cardiogenic shock, left ventricular ejection fraction < 30% and operation before 2007 were noted as independent predictors of conversion. The overall hospital mortality rate was 5.1%: 4.8% in LMCAS < 50%, 4.5% in LMCAS 50-90%, and 9.4% in LMCAS ≥ 90%. Operation status, cardiogenic shock, left ventricular ejection fraction < 30% and intraoperative conversion were observed to be independent predictors of mortality. However, LMCAS did not predict either conversion or hospital mortality.
CONCLUSIONS: LMCAS ≥ 90% was not an independent predictor of intraoperative conversion or hospital mortality in OPCAB. KEY WORDS: Conversion; Left main coronary artery stenosis; Off-pump coronary artery bypass.

Entities:  

Year:  2014        PMID: 27122830      PMCID: PMC4804846          DOI: 10.6515/acs20140929a

Source DB:  PubMed          Journal:  Acta Cardiol Sin        ISSN: 1011-6842            Impact factor:   2.672


  25 in total

1.  On-pump versus off-pump coronary-artery bypass surgery.

Authors:  A Laurie Shroyer; Frederick L Grover; Brack Hattler; Joseph F Collins; Gerald O McDonald; Elizabeth Kozora; John C Lucke; Janet H Baltz; Dimitri Novitzky
Journal:  N Engl J Med       Date:  2009-11-05       Impact factor: 91.245

2.  On-pump and off-pump coronary artery bypass grafting in patients with left main stem disease: a propensity score analysis.

Authors:  Michele Murzi; Massimo Caputo; Giuseppe Aresu; Simon Duggan; Antonio Miceli; Mattia Glauber; Gianni D Angelini
Journal:  J Thorac Cardiovasc Surg       Date:  2011-08-16       Impact factor: 5.209

Review 3.  Off-pump vs. on-pump coronary artery bypass surgery: an updated meta-analysis and meta-regression of randomized trials.

Authors:  Jonathan Afilalo; Mandana Rasti; Samuel M Ohayon; Avi Shimony; Mark J Eisenberg
Journal:  Eur Heart J       Date:  2011-10-10       Impact factor: 29.983

4.  Off-Pump Coronary Artery Bypass Grafting is Associated With Reduced Operative Mortality and In-Hospital Adverse Events in Patients With Left Main Coronary Artery Disease.

Authors:  Eric L Sarin; John D Puskas; Patrick D Kilgo; Vinod H Thourani; Robert A Guyton; Omar M Lattouf
Journal:  Innovations (Phila)       Date:  2009-03

5.  Off-pump coronary artery bypass surgery for critical left main stem disease: safety, efficacy and outcome.

Authors:  M Yeatman; M Caputo; R Ascione; F Ciulli; G D Angelini
Journal:  Eur J Cardiothorac Surg       Date:  2001-03       Impact factor: 4.191

6.  Risk factors for conversion to cardiopulmonary bypass during off-pump coronary artery bypass surgery.

Authors:  Ritam Chowdhury; Darcy White; Patrick Kilgo; John D Puskas; Vinod H Thourani; Edward P Chen; Omar M Lattouf; William A Cooper; Richard J Myung; Robert A Guyton; Michael E Halkos
Journal:  Ann Thorac Surg       Date:  2012-04-13       Impact factor: 4.330

7.  Intraaortic balloon pump therapy facilitates posterior vessel off-pump coronary artery bypass grafting in high-risk patients.

Authors:  K B Kim; C Lim; H Ahn; J K Yang
Journal:  Ann Thorac Surg       Date:  2001-06       Impact factor: 4.330

8.  Does the number of grafts influence surgeon choice and patient benefit of off-pump over conventional on-pump coronary artery revascularization in multivessel coronary artery disease?

Authors:  Omar M Lattouf; John D Puskas; Vinod H Thourani; Joseph Noora; Patrick D Kilgo; Robert A Guyton
Journal:  Ann Thorac Surg       Date:  2007-11       Impact factor: 4.330

9.  Surgical volume and outcomes of off-pump coronary artery bypass graft surgery: Does it matter?

Authors:  Suma H Konety; Gary E Rosenthal; Mary S Vaughan-Sarrazin
Journal:  J Thorac Cardiovasc Surg       Date:  2009-03-25       Impact factor: 5.209

10.  Off-pump coronary bypass grafting is safe and efficient in patients with left main disease and higher EuroScore.

Authors:  George Naveen Thomas; Eliana Cecilia Martinez; Felix Woitek; Maximilian Y Emmert; Hisashi Sakaguchi; Sonja Muecke; Chuen Neng Lee; Theo Kofidis
Journal:  Eur J Cardiothorac Surg       Date:  2009-06-11       Impact factor: 4.191

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