Literature DB >> 27122117

Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis by inhibiting RIPK1.

I-Fang Hsin1, Erica Montano1, Ekihiro Seki1.   

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Year:  2016        PMID： 27122117      PMCID： PMC4917439          DOI： 10.1002/hep.28627

Source DB:  PubMed          Journal:  Hepatology        ISSN： 0270-9139            Impact factor:   17.425


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  7 in total

1.  RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.

Authors:  Marius Dannappel; Katerina Vlantis; Snehlata Kumari; Apostolos Polykratis; Chun Kim; Laurens Wachsmuth; Christina Eftychi; Juan Lin; Teresa Corona; Nicole Hermance; Matija Zelic; Petra Kirsch; Marijana Basic; Andre Bleich; Michelle Kelliher; Manolis Pasparakis
Journal:  Nature       Date:  2014-08-17       Impact factor: 49.962

2.  Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma.

Authors:  Tom Luedde; Naiara Beraza; Vasileios Kotsikoris; Geert van Loo; Arianna Nenci; Rita De Vos; Tania Roskams; Christian Trautwein; Manolis Pasparakis
Journal:  Cancer Cell       Date:  2007-02       Impact factor: 31.743

Review 3.  Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1.

Authors:  Scott J Justus; Adrian T Ting
Journal:  Immunol Rev       Date:  2015-07       Impact factor: 12.988

4.  NEMO expression in human hepatocellular carcinoma and its association with clinical outcome.

Authors:  Ariane Aigelsreiter; Johannes Haybaeck; Silvia Schauer; Tobias Kiesslich; Kira Bettermann; Antonia Griessbacher; Tatjana Stojakovic; Thomas Bauernhofer; Hellmut Samonigg; Peter Kornprat; Carolin Lackner; Martin Pichler
Journal:  Hum Pathol       Date:  2011-12-15       Impact factor: 3.466

5.  Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout.

Authors:  H Ehlken; S Krishna-Subramanian; L Ochoa-Callejero; V Kondylis; N E Nadi; B K Straub; P Schirmacher; H Walczak; G Kollias; M Pasparakis
Journal:  Cell Death Differ       Date:  2014-06-27       Impact factor: 15.828

6.  NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling.

Authors:  D Legarda-Addison; H Hase; M A O'Donnell; A T Ting
Journal:  Cell Death Differ       Date:  2009-04-17       Impact factor: 15.828

7.  NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.

Authors:  Vangelis Kondylis; Apostolos Polykratis; Hanno Ehlken; Laura Ochoa-Callejero; Beate Katharina Straub; Santosh Krishna-Subramanian; Trieu-My Van; Harald-Morten Curth; Nicole Heise; Falk Weih; Ulf Klein; Peter Schirmacher; Michelle Kelliher; Manolis Pasparakis
Journal:  Cancer Cell       Date:  2015-11-09       Impact factor: 31.743
  7 in total
  1 in total

1.  Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species.

Authors:  Wenquan Liang; Aizhen Cai; Guozhu Chen; Hongqing Xi; Xiaosong Wu; Jianxin Cui; Kecheng Zhang; Xudong Zhao; Jiyun Yu; Bo Wei; Lin Chen
Journal:  Sci Rep       Date:  2016-12-01       Impact factor: 4.379
  1 in total

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