Literature DB >> 27122000

Pieter Cullis: an outstanding lipid biophysicist, drug delivery scientist, educator, and entrepreneur.

Leaf Huang1, Lei Miao1.   

Abstract

There are much said about Pieter Cullis in this special volume honoring him. He was the pioneer to study the role of hexagonal HII phase in membrane fusion and the one who applied this concept for the design of lipid nanoparticles. He was also the first to utilize remote loading techniques for the delivery of amphipathic bases. At the same time, he is a tremendous entrepreneur and an excellent mentor. He is, without doubt, an exceptional scientist and set us an excellent model to follow.

Entities:  

Keywords:  Doxil; Pieter Cullis; hexagonal HII phase; remote loading

Mesh：

Substances：

Year:  2016        PMID： 27122000      PMCID： PMC5530756          DOI： 10.3109/1061186X.2016.1172590

Source DB:  PubMed          Journal:  J Drug Target        ISSN： 1026-7158            Impact factor:   5.121


  18 in total

1.  Remote loading of aloe emodin in gemini-based cationic liposomes.

Authors:  Chiara Giuliani; Barbara Altieri; Cecilia Bombelli; Luciano Galantini; Giovanna Mancini; Annarita Stringaro
Journal:  Langmuir       Date:  2014-12-23       Impact factor: 3.882

2.  siRNA LNCs--a novel platform of lipid nanocapsules for systemic siRNA administration.

Authors:  Stephanie David; Pauline Resnier; Alexis Guillot; Bruno Pitard; Jean-Pierre Benoit; Catherine Passirani
Journal:  Eur J Pharm Biopharm       Date:  2012-02-21       Impact factor: 5.571

3.  Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice.

Authors:  L D Mayer; L C Tai; D S Ko; D Masin; R S Ginsberg; P R Cullis; M B Bally
Journal:  Cancer Res       Date:  1989-11-01       Impact factor: 12.701

4.  Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient.

Authors:  L D Mayer; M B Bally; P R Cullis
Journal:  Biochim Biophys Acta       Date:  1986-05-09

Review 5.  Roles of lipid polymorphism in intracellular delivery.

Authors:  I M Hafez; P R Cullis
Journal:  Adv Drug Deliv Rev       Date:  2001-04-25       Impact factor: 15.470

6.  The mechanism of lamellar-to-inverted hexagonal phase transitions in phosphatidylethanolamine: implications for membrane fusion mechanisms.

Authors:  D P Siegel; R M Epand
Journal:  Biophys J       Date:  1997-12       Impact factor: 4.033

7.  Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol.

Authors:  T D Madden; A S Janoff; P R Cullis
Journal:  Chem Phys Lipids       Date:  1990-02       Impact factor: 3.329

8.  Lipid polymorphism and the roles of lipids in membranes.

Authors:  P R Cullis; M J Hope; C P Tilcock
Journal:  Chem Phys Lipids       Date:  1986 Jun-Jul       Impact factor: 3.329

9.  Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients.

Authors:  E Maurer-Spurej; K F Wong; N Maurer; D B Fenske; P R Cullis
Journal:  Biochim Biophys Acta       Date:  1999-01-12

10.  In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE.

Authors:  N J Caplen; E Kinrade; F Sorgi; X Gao; D Gruenert; D Geddes; C Coutelle; L Huang; E W Alton; R Williamson
Journal:  Gene Ther       Date:  1995-11       Impact factor: 5.250
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