Literature DB >> 27119628

Reductionism Is Dead: Long Live Reductionism! Systems Modeling Needs Reductionist Experiments.

James R Faeder1, Penelope A Morel2.   

Abstract

Year:  2016        PMID： 27119628      PMCID： PMC4850343          DOI： 10.1016/j.bpj.2016.03.025

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


× No keyword cloud information.
  13 in total

Review 1.  The role of T cell receptor signaling thresholds in guiding T cell fate decisions.

Authors:  Julie Zikherman; Byron Au-Yeung
Journal:  Curr Opin Immunol       Date:  2015-02-06       Impact factor: 7.486

Review 2.  Non-catalytic tyrosine-phosphorylated receptors.

Authors:  Omer Dushek; Jesse Goyette; P Anton van der Merwe
Journal:  Immunol Rev       Date:  2012-11       Impact factor: 12.988

3.  The 21- and 23-kD forms of TCR zeta are generated by specific ITAM phosphorylations.

Authors:  N S van Oers; B Tohlen; B Malissen; C R Moomaw; S Afendis; C A Slaughter
Journal:  Nat Immunol       Date:  2000-10       Impact factor: 25.606

4.  Ultrasensitivity in multisite phosphorylation of membrane-anchored proteins.

Authors:  Omer Dushek; P Anton van der Merwe; Vahid Shahrezaei
Journal:  Biophys J       Date:  2011-03-02       Impact factor: 4.033

Review 5.  Organization of proximal signal initiation at the TCR:CD3 complex.

Authors:  Clifford S Guy; Dario A A Vignali
Journal:  Immunol Rev       Date:  2009-11       Impact factor: 12.988

Review 6.  T-cell receptor signal transmission: who gives an ITAM?

Authors:  Lisa A Pitcher; Nicolai S C van Oers
Journal:  Trends Immunol       Date:  2003-10       Impact factor: 16.687

7.  Biophysical mechanism of T-cell receptor triggering in a reconstituted system.

Authors:  John R James; Ronald D Vale
Journal:  Nature       Date:  2012-07-05       Impact factor: 49.962

8.  In vitro membrane reconstitution of the T-cell receptor proximal signaling network.

Authors:  Enfu Hui; Ronald D Vale
Journal:  Nat Struct Mol Biol       Date:  2014-01-26       Impact factor: 15.369

9.  Multisite Phosphorylation Modulates the T Cell Receptor ζ-Chain Potency but not the Switchlike Response.

Authors:  Himadri Mukhopadhyay; Ben de Wet; Lara Clemens; Philip K Maini; Jun Allard; P Anton van der Merwe; Omer Dushek
Journal:  Biophys J       Date:  2016-04-26       Impact factor: 4.033

10.  Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity.

Authors:  Himadri Mukhopadhyay; Shaun-Paul Cordoba; Philip K Maini; P Anton van der Merwe; Omer Dushek
Journal:  PLoS Comput Biol       Date:  2013-03-28       Impact factor: 4.475
View more
  3 in total

1.  Screening for Combination Cancer Therapies With Dynamic Fuzzy Modeling and Multi-Objective Optimization.

Authors:  Simone Spolaor; Martijn Scheve; Murat Firat; Paolo Cazzaniga; Daniela Besozzi; Marco S Nobile
Journal:  Front Genet       Date:  2021-03-31       Impact factor: 4.599

2.  Thrombin-Fibrinogen In Vitro Flow Model of Thrombus Growth in Cerebral Aneurysms.

Authors:  Malebogo N Ngoepe; Etheresia Pretorius; Ilunga J Tshimanga; Zahra Shaikh; Yiannis Ventikos; Wei Hua Ho
Journal:  TH Open       Date:  2021-05-12

3.  Fuzzy modeling and global optimization to predict novel therapeutic targets in cancer cells.

Authors:  Marco S Nobile; Giuseppina Votta; Roberta Palorini; Simone Spolaor; Humberto De Vitto; Paolo Cazzaniga; Francesca Ricciardiello; Giancarlo Mauri; Lilia Alberghina; Ferdinando Chiaradonna; Daniela Besozzi
Journal:  Bioinformatics       Date:  2020-04-01       Impact factor: 6.937
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.