Literature DB >> 27118483

Association between metabolic syndrome and 10-year risk of developing cardiovascular disease in a Nigerian population.

Victor M Oguoma1, Ezekiel U Nwose2, Timothy C Skinner3, Ross S Richards4, Kester A Digban5, Innocent C Onyia6.   

Abstract

BACKGROUND: Prevalence of metabolic syndrome (MetS) and consequential cardiovascular disease (CVD) events are on the increase in Nigeria. The study aimed to identify the prevalence of 10-year CVD risk in a Nigerian population and assess its relationship with different indices of MetS.
METHOD: A cross-sectional study was carried out on apparently healthy persons aged 18 years of age or older. Ten-year risk was calculated using the ATPIII/Framingham criteria. Subjects with risk score <10% were considered as having low risk, 10-20% moderate risk and >20% at high risk of developing CVD in 10 years. MetS was defined based on the Joint Scientific Statement on Harmonizing the MetS. RESULT: Of the 211 subjects, mean age was 51.3±17.3 years. Average risk of developing CVD in the next 10 years was 3.7±5.3%. Prevalence of low, moderate and high risk of developing CVD among study participants was 86.3% (95% CI 82.0-91.3%), 11.8% (95% CI 6.9-16.1%) and 1.9% (95% CI 0.0-3.8%), respectively. Prevalence of MetS was 26.7% (95% CI 21.0-33.3%). There was poor agreement between MetS and the CVD risk scores (kappa=0.209, p=0.001)
CONCLUSIONS: The results showed that complementary use of MetS and CVD risk score is imperative, as there is indication of risk in individuals without MetS. Also a large proportion of the study population requires lifestyle intervention. These findings provide the evidence necessary to tailor public health interventions in this population, especially towards younger age groups.
© The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  10-year CVD risk; ATPIII/Framingham risk score; CVD risk factors; Metabolic syndrome; Nigeria; Risk assessment tool

Mesh:

Year:  2016        PMID: 27118483     DOI: 10.1093/inthealth/ihw013

Source DB:  PubMed          Journal:  Int Health        ISSN: 1876-3405            Impact factor:   2.473


  3 in total

1.  Cardiovascular disease risk factors in a Nigerian population with impaired fasting blood glucose level and diabetes mellitus.

Authors:  Victor M Oguoma; Ezekiel U Nwose; Ifeoma I Ulasi; Adeseye A Akintunde; Ekene E Chukwukelu; Phillip T Bwititi; Ross S Richards; Timothy C Skinner
Journal:  BMC Public Health       Date:  2017-01-06       Impact factor: 3.295

2.  Collaborative Molecular Epidemiology Study of Metabolic Dysregulation, DNA Methylation, and Breast Cancer Risk Among Nigerian Women: MEND Study Objectives and Design.

Authors:  Tomi Akinyemiju; Omolola Salako; Adetola Daramola; Olusegun Alatise; Adewale Adeniyi; Gabriel Ogun; Omobolaji Ayandipo; Thomas Olajide; Olalekan Olasehinde; Olukayode Arowolo; Adewale Adisa; Oludolapo Afuwape; Aralola Olusanya; Aderemi Adegoke; Akinlolu Ojo; Trygve Tollefsbol; Donna Arnett
Journal:  J Glob Oncol       Date:  2019-06

3.  Association between high-fasting insulin levels and metabolic syndrome in non-diabetic middle-aged and elderly populations: a community-based study in Taiwan.

Authors:  Yun-Hung Chen; Yu-Chien Lee; Yu-Chung Tsao; Mei-Chun Lu; Hai-Hua Chuang; Wei-Chung Yeh; I-Shiang Tzeng; Jau-Yuan Chen
Journal:  BMJ Open       Date:  2018-05-03       Impact factor: 2.692

  3 in total

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