Francesco Massari1, Massimo Iacoviello2, Pietro Scicchitano3, Filippo Mastropasqua4, Pietro Guida5, Graziano Riccioni6, Giuseppe Speziale7, Pasquale Caldarola8, Marco Matteo Ciccone2, Salvatore Di Somma9. 1. Cardiology Section, "F. Perinei" Hospital, Bari, Italy. 2. Section of Cardiovascular Diseases, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy. 3. Cardiology Section, "F. Perinei" Hospital, Bari, Italy. Electronic address: piero.sc@hotmail.it. 4. Cardiology Section, IRCCS "S Maugeri" Foundation, Cassano Murge, Bari, Italy. 5. Cardiology Section, IRCCS "S. Maugeri" Foundation, Cassano Murge, Bari, Italy. 6. Cardiology Unit, San Camillo De Lellis Hospital, Manfredonia, Foggia, Italy. 7. Heart Surgery Department, Villa ANTHEA Hospital, Bari, Italy. 8. Cardiology Section, "S. Paolo" Hospital, Bari, Italy. 9. Emergency Department, Sant'Andrea Hospital, Medical-Surgery Sciences and Translational Medicine, University La Sapienza, Rome, Italy.
Abstract
OBJECTIVE: To evaluate the role of bioelectrical impedance vector analysis (BIVA) and brain natriuretic peptide (BNP) in detecting peripheral congestion in heart failure (HF). BACKGROUND: BIVA/BNP are biomarkers for congestion in acute (ADHF) and chronic HF. METHODS: 487 ADHF and 413 chronic HF patients underwent BIVA and BNP tests. RESULTS: BIVA was more accurate than BNP in detecting peripheral congestion both in ADHF (AUC 0.88 vs 0.57 respectively; p < 0.001) and chronic HF patients (AUC 0.89 vs 0.68, respectively; p < 0.001). In ADHF patients, the optimal BNP cut-off for discriminating presence or absence of edema was >870 pg/mL (PPV = 48% and NPV = 58%) whereas in chronic HF it was >216 pg/mL (PPV = 18% and NPV = 95%). The BIVA detected edema when the vector fell into the lower pole of 75th percentile tolerance ellipse (PPV = 84% and NPV = 78%) in ADHF, the lower pole of 50% (PPV = 68% and NPV = 95%) in chronic HF. CONCLUSIONS: In HF patients, BIVA is an easy, fast technique to assess peripheral congestion, and is even more accurate than BNP.
OBJECTIVE: To evaluate the role of bioelectrical impedance vector analysis (BIVA) and brain natriuretic peptide (BNP) in detecting peripheral congestion in heart failure (HF). BACKGROUND:BIVA/BNP are biomarkers for congestion in acute (ADHF) and chronic HF. METHODS: 487 ADHF and 413 chronic HF patients underwent BIVA and BNP tests. RESULTS:BIVA was more accurate than BNP in detecting peripheral congestion both in ADHF (AUC 0.88 vs 0.57 respectively; p < 0.001) and chronic HF patients (AUC 0.89 vs 0.68, respectively; p < 0.001). In ADHFpatients, the optimal BNP cut-off for discriminating presence or absence of edema was >870 pg/mL (PPV = 48% and NPV = 58%) whereas in chronic HF it was >216 pg/mL (PPV = 18% and NPV = 95%). The BIVA detected edema when the vector fell into the lower pole of 75th percentile tolerance ellipse (PPV = 84% and NPV = 78%) in ADHF, the lower pole of 50% (PPV = 68% and NPV = 95%) in chronic HF. CONCLUSIONS: In HF patients, BIVA is an easy, fast technique to assess peripheral congestion, and is even more accurate than BNP.
Authors: Fiorangelo De Ieso; Markus Reinhold Mutke; Noe Karl Brasier; Christina Janitha Raichle; Bettina Keller; Celine Sucker; Khaled Abdelhamid; Tiziano Bloch; Pamela Reissenberger; Ladina Schönenberg; Sandro Kevin Fischer; Jonas Saboz; Nora Weber; Sabine Schädelin; Nicole Bruni; Patrick R Wright; Jens Eckstein Journal: ESC Heart Fail Date: 2021-10-13
Authors: Stephen J Hankinson; Charles H Williams; Van-Khue Ton; Stephen S Gottlieb; Charles C Hong Journal: Expert Rev Med Devices Date: 2020-07-13 Impact factor: 3.166
Authors: Pietro Scicchitano; Claudio Paolillo; Micaela De Palo; Angela Potenza; Silvia Abruzzese; Marco Basile; Antonia Cannito; Maria Tangorra; Piero Guida; Pasquale Caldarola; Marco Matteo Ciccone; Francesco Massari Journal: J Cardiovasc Dev Dis Date: 2022-02-24