Beth M Isaac1, Abbey Masonbrink2, Joseph Kennedy2, Sharon K Greene3, Robin R Hennessy4, Jennifer B Rosen3, Lisa Trieu3, Stephanie Ngai3, Stephen S Morse5, Don Weiss3. 1. Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, NY; Mailman School of Public Health, Columbia University, New York, NY. Electronic address: bisaac@health.nyc.gov. 2. Division of Epidemiology, New York City Department of Health and Mental Hygiene, Queens, NY. 3. Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, NY. 4. Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, NY; Division of Sexually Transmitted Disease Prevention, Centers for Disease Control and Prevention, Atlanta, GA. 5. Mailman School of Public Health, Columbia University, New York, NY.
Abstract
OBJECTIVE: To determine rates of reportable bacterial infections among infants in New York City and identify populations at risk and preventable causes of morbidity. STUDY DESIGN: This retrospective cohort study matched live births in New York City from 2001-2009 to reported cases of bacterial infections among infants less than 1 year of age. Characteristics recorded on birth certificates were compared between infants with bacterial enteric infection, bacterial nonenteric infection, and no reportable bacterial infection. Multinomial logistic regression and multivariable logistic regression were used to identify risk factors for infection. RESULTS: Bacterial infection was reported in 4.6 cases per 1000 live births. Of 4524 infants with a reportable infection, the majority (2880, 63%) had an enteric infection. Asian/Pacific Islanders in Brooklyn were the borough-level race/ethnic group with the highest enteric infection rate (8.5 per 1000 live births). Citywide, infants with enteric infections were disproportionately male, from higher poverty neighborhoods, born to foreign-born mothers, and enrolled in Special Supplemental Food Program for Women, Infants, and Children or Medicaid. In contrast, infants with nonenteric infections were more likely to have low birthweight and mothers characterized by US birth and black race or white Hispanic race/ethnicity. CONCLUSIONS: Distinct patterns of risk factors for enteric and nonenteric bacterial infections among infants were identified. The results suggest that infants born to Asian/Pacific Islander mothers residing in Brooklyn should be a focus of enteric disease prevention. More research is necessary to better understand what behaviors increase the risk of enteric disease in this population.
OBJECTIVE: To determine rates of reportable bacterial infections among infants in New York City and identify populations at risk and preventable causes of morbidity. STUDY DESIGN: This retrospective cohort study matched live births in New York City from 2001-2009 to reported cases of bacterial infections among infants less than 1 year of age. Characteristics recorded on birth certificates were compared between infants with bacterial enteric infection, bacterial nonenteric infection, and no reportable bacterial infection. Multinomial logistic regression and multivariable logistic regression were used to identify risk factors for infection. RESULTS:Bacterial infection was reported in 4.6 cases per 1000 live births. Of 4524 infants with a reportable infection, the majority (2880, 63%) had an enteric infection. Asian/Pacific Islanders in Brooklyn were the borough-level race/ethnic group with the highest enteric infection rate (8.5 per 1000 live births). Citywide, infants with enteric infections were disproportionately male, from higher poverty neighborhoods, born to foreign-born mothers, and enrolled in Special Supplemental Food Program for Women, Infants, and Children or Medicaid. In contrast, infants with nonenteric infections were more likely to have low birthweight and mothers characterized by US birth and black race or white Hispanic race/ethnicity. CONCLUSIONS: Distinct patterns of risk factors for enteric and nonenteric bacterial infections among infants were identified. The results suggest that infants born to Asian/Pacific Islander mothers residing in Brooklyn should be a focus of enteric disease prevention. More research is necessary to better understand what behaviors increase the risk of enteric disease in this population.
Authors: Emma Sherwood; Stefania Vergnano; Isona Kakuchi; Michael G Bruce; Suman Chaurasia; Samara David; Angela Dramowski; Scarlett Georges; Rebecca Guy; Theresa Lamagni; Daniel Levy-Bruhl; Outi Lyytikäinen; Monika Naus; Jennifer Onukwube Okaro; Oddvar Oppegaard; Didrik F Vestrheim; Tammy Zulz; Andrew C Steer; Chris A Van Beneden; Anna C Seale Journal: Lancet Infect Dis Date: 2022-04-04 Impact factor: 71.421