Literature DB >> 27116606

Correction: Nitro-Arachidonic Acid Prevents Angiotensin II Induced Mitochondrial Dysfunction in Kidney Proximal Tubular Cells.

Beatriz Sánchez-Calvo, Adriana Cassina, Natalia Rios, Gonzalo Peluffo, José Boggia, Rafael Radi, Homero Rubbo, Andrés Trostchansky.   

Abstract

[This corrects the article DOI: 10.1371/journal.pone.0150459.].

Entities:  

Year:  2016        PMID: 27116606      PMCID: PMC4846006          DOI: 10.1371/journal.pone.0154651

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


The following information is missing from the funding section: This work was supported by grants from Fondo Clemente Estable-ANII (FCE_6353) to AT and (FCE_6363) to GP, CSIC-Grupos (Uruguay) to HR and RR. BSC was supported by a postdoctoral fellowship by ANII-Uruguay. NR was partially supported by a fellowship from Sistema Nacional de Becas-ANII. In Panel B of Fig 1, the x-axis is missing. Please see the corrected Fig 1 here.
Fig 1

ANG II-mediatedO2.-production is inhibited by NO2-AA.

(A) Dehydroethydium (DHE) oxidation as an index of O2.- production in ANG II-stimulated HK-2 cells (1x106 cells) was determined by HPLC with fluorescence detection (λem = 595 nm, λexc = 510 nm). Cells were preincubated 30 min with vehicle, 10 μM NO2-AA or 10 μM AA and then exposed to DHE in simultaneous with 0.1 μM ANG II for 3 h. Quantitative analysis, expressed as the mean fold change than control condition without ANG II stimulation ± SEM, n = 3 of 2-OH-Et+ (B) and Et+ (C) are shown. *, # correspond to significant data relative to control and ANG II-treated cells, respectively (p<0.05).

ANG II-mediatedO2.-production is inhibited by NO2-AA.

(A) Dehydroethydium (DHE) oxidation as an index of O2.- production in ANG II-stimulated HK-2 cells (1x106 cells) was determined by HPLC with fluorescence detection (λem = 595 nm, λexc = 510 nm). Cells were preincubated 30 min with vehicle, 10 μM NO2-AA or 10 μM AA and then exposed to DHE in simultaneous with 0.1 μM ANG II for 3 h. Quantitative analysis, expressed as the mean fold change than control condition without ANG II stimulation ± SEM, n = 3 of 2-OH-Et+ (B) and Et+ (C) are shown. *, # correspond to significant data relative to control and ANG II-treated cells, respectively (p<0.05).
  1 in total

1.  Nitro-Arachidonic Acid Prevents Angiotensin II-Induced Mitochondrial Dysfunction in a Cell Line of Kidney Proximal Tubular Cells.

Authors:  Beatriz Sánchez-Calvo; Adriana Cassina; Natalia Rios; Gonzalo Peluffo; José Boggia; Rafael Radi; Homero Rubbo; Andres Trostchansky
Journal:  PLoS One       Date:  2016-03-04       Impact factor: 3.240

  1 in total

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