Literature DB >> 27115078

Simultaneous fluorescence imaging of selenol and hydrogen peroxide under normoxia and hypoxia in HepG2 cells and in vivo.

Xiaojun Liu1, Bo Hu1, Ranran Cheng1, Fanpeng Kong1, Xiaohong Pan1, Kehua Xu1, Bo Tang1.   

Abstract

Based on the rapid substitution reaction of the Au-S bond by selenol, we designed and synthesized a nanoprobe 5-FAM-peptide-AuNPs for selenol. Real-time imaging shows that this probe together with the molecular probe QCy7-H2O2 is able to simultaneously and differentially monitor the concentrations of selenol and H2O2 in living cells and in vivo.

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Year:  2016        PMID： 27115078     DOI： 10.1039/c6cc02111e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  A Fluorescent Probe for the Specific Staining of Cysteine Containing Proteins and Thioredoxin Reductase in SDS-PAGE.

Authors:  Yuning Liu; Yanan Yu; Qingshi Meng; Xueting Jia; Jiawei Zhu; Chaohua Tang; Qingyu Zhao; Xiaohui Feng; Junmin Zhang
Journal:  Biosensors (Basel)       Date:  2021-04-23

2.  Monitoring NAD(P)H by an ultrasensitive fluorescent probe to reveal reductive stress induced by natural antioxidants in HepG2 cells under hypoxia.

Authors:  Xiaohong Pan; Yuehui Zhao; Tingting Cheng; Aishan Zheng; Anbin Ge; Lixin Zang; Kehua Xu; Bo Tang
Journal:  Chem Sci       Date:  2019-07-19       Impact factor: 9.825

3.  Double-ratiometric fluorescence imaging of H2Se and O2˙- under hypoxia for exploring Na2SeO3-induced HepG2 cells' apoptosis.

Authors:  Xiaonan Gao; Wenfei Guo; Lihong Ge; Fanpeng Kong; Kehua Xu; Bo Tang
Journal:  RSC Adv       Date:  2018-12-07       Impact factor: 4.036
  3 in total

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