| Literature DB >> 27114333 |
Kalyanam Shivkumar1, Olujimi A Ajijola1, Inder Anand2, J Andrew Armour1, Peng-Sheng Chen3, Murray Esler4, Gaetano M De Ferrari5, Michael C Fishbein6, Jeffrey J Goldberger7, Ronald M Harper8, Michael J Joyner9, Sahib S Khalsa10, Rajesh Kumar11, Richard Lane12, Aman Mahajan13, Sunny Po14,15, Peter J Schwartz16, Virend K Somers9, Miguel Valderrabano17, Marmar Vaseghi1, Douglas P Zipes18.
Abstract
The autonomic nervous system regulates all aspects of normal cardiac function, and is recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As such, the value of neuroscience-based cardiovascular therapeutics is increasingly evident. This White Paper reviews the current state of understanding of human cardiac neuroanatomy, neurophysiology, pathophysiology in specific disease conditions, autonomic testing, risk stratification, and neuromodulatory strategies to mitigate the progression of cardiovascular diseases.Entities:
Mesh:
Year: 2016 PMID: 27114333 PMCID: PMC4945719 DOI: 10.1113/JP271870
Source DB: PubMed Journal: J Physiol ISSN: 0022-3751 Impact factor: 5.182