Nino Hirnschall1, Christoph Leisser1, Stephan Radda1, Sophie Maedel1, Oliver Findl2. 1. From the Vienna Institute for Research in Ocular Surgery, A Karl Landsteiner Institute (Hirnschall, Leisser, Radda, Mädel, Findl), Hanusch Hospital, Vienna, Austria, and Moorfields Eye Hospital NHS Foundation Trust (Findl), London, United Kingdom. 2. From the Vienna Institute for Research in Ocular Surgery, A Karl Landsteiner Institute (Hirnschall, Leisser, Radda, Mädel, Findl), Hanusch Hospital, Vienna, Austria, and Moorfields Eye Hospital NHS Foundation Trust (Findl), London, United Kingdom. Electronic address: oliver@findl.at.
Abstract
PURPOSE: To assess the sensitivity and specificity for detecting macular disease with a new optical biometry device with swept-source optical coherence tomography (SS-OCT) used before cataract surgery. SETTING: Hanusch Hospital, Vienna, Austria. DESIGN: Consecutive case series. METHODS: This study included patients with or without macular disease. All patients were scanned using the new biometry device (IOLMaster 700), which allows a 1.0 mm central retinal scan using SS-OCT technology. Also, all eyes were assessed using a dedicated retinal OCT device (RTVue) on the same day. Two experienced examiners and 1 ophthalmology resident graded all scans individually. Sensitivity and specificity for detecting macular disease were assessed, as were the receiver operating characteristic curves. RESULTS: Of the 125 eyes included, 5 were excluded from the analysis, 65 had a macular disease, and 55 were healthy. The sensitivity of the biometry device was moderate (between 42% and 68%), and the specificity was high (89% to 98%). Intraobserver reproducibility for assessing the biometry device was 88.3%. CONCLUSIONS: The biometry device with SS-OCT provided useful information concerning the macula, especially for intraretinal fluid and macular holes. However, it cannot replace a macular OCT device. FINANCIAL DISCLOSURE: None of the authors has a financial or proprietary interest in any material or method mentioned.
PURPOSE: To assess the sensitivity and specificity for detecting macular disease with a new optical biometry device with swept-source optical coherence tomography (SS-OCT) used before cataract surgery. SETTING: Hanusch Hospital, Vienna, Austria. DESIGN: Consecutive case series. METHODS: This study included patients with or without macular disease. All patients were scanned using the new biometry device (IOLMaster 700), which allows a 1.0 mm central retinal scan using SS-OCT technology. Also, all eyes were assessed using a dedicated retinal OCT device (RTVue) on the same day. Two experienced examiners and 1 ophthalmology resident graded all scans individually. Sensitivity and specificity for detecting macular disease were assessed, as were the receiver operating characteristic curves. RESULTS: Of the 125 eyes included, 5 were excluded from the analysis, 65 had a macular disease, and 55 were healthy. The sensitivity of the biometry device was moderate (between 42% and 68%), and the specificity was high (89% to 98%). Intraobserver reproducibility for assessing the biometry device was 88.3%. CONCLUSIONS: The biometry device with SS-OCT provided useful information concerning the macula, especially for intraretinal fluid and macular holes. However, it cannot replace a macular OCT device. FINANCIAL DISCLOSURE: None of the authors has a financial or proprietary interest in any material or method mentioned.
Authors: Daniele Tognetto; Marco R Pastore; Chiara De Giacinto; Riccardo Merli; Marco Franzon; Rossella D'Aloisio; Lorenzo Belfanti; Rosa Giglio; Gabriella Cirigliano Journal: Sci Rep Date: 2019-07-09 Impact factor: 4.379