Literature DB >> 27111763

Variations in Sagittal Alignment Parameters Based on Age: A Prospective Study of Asymptomatic Volunteers Using Full-Body Radiographs.

Sravisht Iyer1, Lawrence G Lenke2,3, Venu M Nemani4, Todd J Albert1,5, Brenda A Sides4, Lionel Nicholas Metz6, Matthew E Cunningham1, Han Jo Kim1,5.   

Abstract

STUDY
DESIGN: Cross-sectional cohort study.
OBJECTIVE: Describe age-stratified normative values of traditional and novel sagittal alignment parameters. SUMMARY OF BACKGROUND DATA: Full-body radiographic techniques can capture coronal and sagittal standing images from the occiput to the foot without stitching or vertical distortion. This provides an ideal method to evaluate measures of global alignment.
METHODS: Adults with no back or neck symptoms were recruited. Age, body mass index, Neck Disability Index, and Oswestry Disability Index scores were recorded. The following parameters were measured: center sacral vertebral line, Occiput-C2 (O-C2) lordosis, cervical lordosis (C2-C7, CL), thoracic kyphosis (T2-12, TK), T2-T5 kyphosis, T5-T12 kyphosis, thoracolumbar kyphosis (T10-L2), lumbar lordosis (L1-S1, LL), sacral slope, pelvic tilt, pelvic incidence (PI), knee flexion angle, global sagittal angle, T1-pelvis angle, C2-S1 sagittal vertical axis (SVA), C7-S1 SVA, Basion-C7 SVA, B-S1 SVA and Basion to the center of the femoral head SVA and PI minus LL. Comparisons of sagittal alignment parameters between different age groups were performed. A Pearson correlation was used to determine relationships.
RESULTS: One hundred fifteen volunteers had imaging suitable for analysis; average age as 50.1 years (range 22-78), average body mass index was 28, average Neck Disability Index was 3.4 ± 4.4, and average Oswestry Disability Index was 1.7 ± 4.9. CL (r = -0.34, P = 0.001), T1-pelvis angle (r = 0.44, P < 0.001), knee flexion angle (r = 0.42, P < 0.001), global sagittal angle (r = 0.56, P < 0.001), and C7 SVA (r = 0.46, P < 0.001) all increased with age. LL decreased with age (r = 0.212, P = 0.039). We were able to establish a chain of correlation extending from the toes to the occiput and report age-based normative values for all parameters.
CONCLUSION: We describe age-based normative sagittal alignment parameters in the adult spine with complete visualization from the occiput to the feet. We describe compensatory changes that occur to maintain sagittal balance. These values may be used as a reference for future studies. LEVEL OF EVIDENCE: 4.

Entities:  

Mesh:

Year:  2016        PMID: 27111763     DOI: 10.1097/BRS.0000000000001642

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  26 in total

1.  Invariance of head-pelvis alignment and compensatory mechanisms for asymptomatic adults older than 49 years.

Authors:  Celia Amabile; Jean-Charles Le Huec; Wafa Skalli
Journal:  Eur Spine J       Date:  2016-11-02       Impact factor: 3.134

Review 2.  Osteotomies in ankylosing spondylitis: where, how many, and how much?

Authors:  Heiko Koller; Juliane Koller; Michael Mayer; Axel Hempfing; Wolfgang Hitzl
Journal:  Eur Spine J       Date:  2017-12-30       Impact factor: 3.134

3.  The standing and sitting sagittal spinopelvic alignment of Chinese young and elderly population: does age influence the differences between the two positions?

Authors:  Siyu Zhou; Zhuoran Sun; Wei Li; Wei Wang; Tong Su; Chengbo Du; Weishi Li
Journal:  Eur Spine J       Date:  2019-10-19       Impact factor: 3.134

4.  Thoracolumbar junction orientation: its impact on thoracic kyphosis and sagittal alignment in both asymptomatic volunteers and symptomatic patients.

Authors:  Hong Joo Moon; Keith H Bridwell; Alekos A Theologis; Micheal P Kelly; Thamrong Lertudomphonwanit; Han Jo Kim; Lawrence G Lenke; Munish C Gupta
Journal:  Eur Spine J       Date:  2019-07-24       Impact factor: 3.134

5.  Associations between potentially modifiable clinical factors and sagittal balance of the spine in older adults from the general population.

Authors:  Larry Cohen; Evangelos Pappas; Kathryn Refshauge; Sarah Dennis; Milena Simic
Journal:  Spine Deform       Date:  2021-11-06

6.  The global alignment in patients with lumbar spinal stenosis: our experience using the EOS full-body images.

Authors:  Jean Yves Lazennec; Dominique Folinais; Samy Bendaya; Marc Antoine Rousseau; Aidin Eslam Pour
Journal:  Eur J Orthop Surg Traumatol       Date:  2016-08-30

7.  Normal variation in sagittal spinal alignment parameters in adult patients: an EOS study using serial imaging.

Authors:  Hwee Weng Dennis Hey; Kian Loong Melvin Tan; Vikaesh Moorthy; Eugene Tze-Chun Lau; Leok-Lim Lau; Gabriel Liu; Hee-Kit Wong
Journal:  Eur Spine J       Date:  2018-01-13       Impact factor: 3.134

8.  Age-based normal sagittal alignment in Chinese asymptomatic adults: establishment of the relationships between pelvic incidence and other parameters.

Authors:  Siyu Zhou; Fei Xu; Wei Wang; Da Zou; Zhuoran Sun; Weishi Li
Journal:  Eur Spine J       Date:  2019-10-29       Impact factor: 3.134

9.  Suboptimal Age-Adjusted Lumbo-Pelvic Mismatch Predicts Negative Cervical-Thoracic Compensation in Obese Patients.

Authors:  Samantha R Horn; Cole A Bortz; Subaraman Ramachandran; Gregory W Poorman; Frank Segreto; Matt Siow; Akhila Sure; Dennis Vasquez-Montes; Bassel Diebo; Jared Tishelman; John Moon; Peter Zhou; Bryan Beaubrun; Shaleen Vira; Cyrus Jalai; Charles Wang; Kartik Shenoy; Omar Behery; Thomas Errico; Virginie Lafage; Aaron Buckland; Peter G Passias
Journal:  Int J Spine Surg       Date:  2019-06-30

10.  In the Relationship Between Change in Kyphosis and Change in Lordosis: Which Drives Which?

Authors:  Bryan Ang; Renaud Lafage; Jonathan Charles Elysée; Tejbir S Pannu; Mathieu Bannwarth; Brandon B Carlson; Frank J Schwab; Han Jo Kim; Virginie Lafage
Journal:  Global Spine J       Date:  2020-04-01
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