Literature DB >> 27111472

FAM129B activates Ras and promotes aerobic glycolysis.

Jong-Ho Lee1, Haitao Ji1, Zhimin Lu1,2,3.   

Abstract

Entities:  

Keywords:  EGFR; FAM129B; PKM2; Ras; p120-RasGAP; the Warburg effect; β-catenin

Mesh：

Substances：

Year:  2016        PMID： 27111472      PMCID： PMC4934072          DOI： 10.1080/15384101.2016.1164581

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Nuclear PKM2 regulates the Warburg effect.

Authors:  Weiwei Yang; Zhimin Lu
Journal:  Cell Cycle       Date:  2013-08-26       Impact factor: 4.534

2.  EGFR phosphorylates FAM129B to promote Ras activation.

Authors:  Haitao Ji; Jong-Ho Lee; Yugang Wang; Yilin Pang; Tao Zhang; Yan Xia; Lianjin Zhong; Jianxin Lyu; Zhimin Lu
Journal:  Proc Natl Acad Sci U S A       Date:  2015-12-31       Impact factor: 11.205

3.  PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.

Authors:  Weiwei Yang; Yan Xia; David Hawke; Xinjian Li; Ji Liang; Dongming Xing; Kenneth Aldape; Tony Hunter; W K Alfred Yung; Zhimin Lu
Journal:  Cell       Date:  2012-08-17       Impact factor: 41.582

4.  EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.

Authors:  Haitao Ji; Ji Wang; Heinz Nika; David Hawke; Susan Keezer; Qingyuan Ge; Bingliang Fang; Xuexun Fang; Dexing Fang; David W Litchfield; Kenneth Aldape; Zhimin Lu
Journal:  Mol Cell       Date:  2009-11-25       Impact factor: 17.970

5.  Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation.

Authors:  Weiwei Yang; Yan Xia; Haitao Ji; Yanhua Zheng; Ji Liang; Wenhua Huang; Xiang Gao; Kenneth Aldape; Zhimin Lu
Journal:  Nature       Date:  2011-12-01       Impact factor: 49.962

6.  ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect.

Authors:  Weiwei Yang; Yanhua Zheng; Yan Xia; Haitao Ji; Xiaomin Chen; Fang Guo; Costas A Lyssiotis; Kenneth Aldape; Lewis C Cantley; Zhimin Lu
Journal:  Nat Cell Biol       Date:  2012-11-25       Impact factor: 28.824

7.  PKM2 functions as a histone kinase.

Authors:  Zhimin Lu
Journal:  Cell Cycle       Date:  2012-10-15       Impact factor: 4.534
  7 in total
  2 in total

1.  Pyruvate kinase M2 (PKM2) expression correlates with prognosis in solid cancers: a meta-analysis.

Authors:  Haiyan Zhu; Hui Luo; Xuejie Zhu; Xiaoli Hu; Lihong Zheng; Xueqiong Zhu
Journal:  Oncotarget       Date:  2017-01-03

Review 2.  The Glycolytic Switch in Tumors: How Many Players Are Involved?

Authors:  Li Yu; Xun Chen; Xueqi Sun; Liantang Wang; Shangwu Chen
Journal:  J Cancer       Date:  2017-09-20       Impact factor: 4.207
  2 in total

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