Literature DB >> 27111073

Adult Native Septic Arthritis in an Inner City Hospital: Effects on Length of Stay.

Jacob Daynes, Matthew F Roth, Mark Zekaj, Ian Hudson, Claire Pearson, Rahul Vaidya.   

Abstract

The objective of this retrospective study was to assess what factors affected length of stay (LOS) in 183 adult patients with native septic arthritis. Diagnosis was based on a representative physical examination, fluid cell count/Gram stain, and organisms isolated from joint fluid culture. Data included demographics, comorbidities, laboratory results, treatment, and discharge times. Joint fluid cultures were positive in 55% (100 of 183) of the patients, and these patients were the subjects of this study. Blood cultures were taken for 65 patients and were positive in 54%; when positive, they were found to be the same as isolates from joint fluid analysis 91% of the time. Pathogens found in joint fluid analysis were as follows: methicillin-susceptible Staphylococcus aureus (MSSA), 44%; methicillin-resistant S aureus (MRSA), 21%; Streptococcus species, 14%; Pseudomonas, 10%; and other organisms, 11%. Surgical washout less than 24 hours from diagnosis affected LOS (12.25 vs 16.96 days for >24 hours; P<.05), but pathogen type and comorbid conditions did not. Average time for culture sensitivities was 4±1 days. Almost half of the patients had MSSA. Delays that could be controlled were getting an early diagnosis and expedient surgical washout of the joint. A lack of insurance and a requirement of intravenous antibiotics prolonged stay, whereas age, sex, and ethnicity did not. Waiting for bacterial sensitivities was a factor that could not be controlled. The authors believe that polymerase chain reaction or other technologies could lead to early diagnosis and expedient surgery. Effective oral antibiotics against resistant organisms would help the patients leave the hospital earlier. [Orthopedics. 2016; 39(4):e674-e679.]. Copyright 2016, SLACK Incorporated.

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Year:  2016        PMID: 27111073     DOI: 10.3928/01477447-20160419-01

Source DB:  PubMed          Journal:  Orthopedics        ISSN: 0147-7447            Impact factor:   1.390


  4 in total

Review 1.  Clinical outcomes involving patients that develop septic arthritis with methicillin sensitive staphylococcus aureus versus methicillin resistant staphylococcus aureus.

Authors:  Kristen Combs; Kyle Cox
Journal:  J Orthop       Date:  2017-11-06

Review 2.  Evaluation and Management of Septic Arthritis and its Mimics in the Emergency Department.

Authors:  Brit Long; Alex Koyfman; Michael Gottlieb
Journal:  West J Emerg Med       Date:  2018-12-06

3.  Group B streptococcus is the most common pathogen for septic arthritis with unique clinical characteristics: data from 12 years retrospective cohort study.

Authors:  Rungkan Ruksasakul; Pongthorn Narongroeknawin; Paijit Assavatanabodee; Sumapa Chaiamnuay
Journal:  BMC Rheumatol       Date:  2019-09-16

4.  Septic Arthritis and the Opioid Epidemic: 1465 Cases of Culture-Positive Native Joint Septic Arthritis From 1990-2018.

Authors:  John J Ross; Kevin L Ard; Narath Carlile
Journal:  Open Forum Infect Dis       Date:  2020-03-12       Impact factor: 3.835

  4 in total

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