Literature DB >> 27109639

Successful clinical treatment and functional immunological normalization of human MALT1 deficiency following hematopoietic stem cell transplantation.

Jacob Rozmus1, Rachel McDonald1, Shan-Yu Fung1, Kate L Del Bel1, Juliana Roden1, Christof Senger2, Kirk R Schultz1, Margaret L McKinnon3, Jeffrey Davis1, Stuart E Turvey4.   

Abstract

MALT1 mutations impair normal NF-κB activation and paracaspase activity to cause a novel combined immunodeficiency. The clinical and immunological phenotype of MALT1 deficiency can be successfully treated with hematopoietic stem cell transplantation following reduced intensity conditioning.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  CARD11–BCL10–MALT1 (CBM) signalosome complex; Combined immunodeficiency; Hematopoietic stem cell transplantation (HSCT); MALT1 mutations; NF-κB; Paracaspase

Mesh：

Substances：

Year:  2016        PMID： 27109639     DOI： 10.1016/j.clim.2016.04.011

Source DB:  PubMed          Journal:  Clin Immunol        ISSN： 1521-6616            Impact factor:   3.969


  8 in total

1.  Progressive B cell depletion in human MALT1 deficiency.

Authors:  Motoshi Sonoda; Masataka Ishimura; Katsuhide Eguchi; Yutaro Yada; Nina Lenhartová; Akira Shiraishi; Tamami Tanaka; Yasunari Sakai; Shouichi Ohga
Journal:  Clin Exp Immunol       Date:  2021-10-07       Impact factor: 4.330

2.  Expanding the Clinical and Immunological Phenotypes and Natural History of MALT1 Deficiency.

Authors:  Asena Pinar Sefer; Hassan Abolhassani; Franziska Ober; Basak Kayaoglu; Sevgi Bilgic Eltan; Altan Kara; Baran Erman; Naz Surucu Yilmaz; Cigdem Aydogmus; Sezin Aydemir; Louis-Marie Charbonnier; Burcu Kolukisa; Gholamreza Azizi; Samaneh Delavari; Tooba Momen; Simuzar Aliyeva; Yasemin Kendir Demirkol; Saban Tekin; Ayca Kiykim; Omer Faruk Baser; Haluk Cokugras; Mayda Gursel; Elif Karakoc-Aydiner; Ahmet Ozen; Daniel Krappmann; Talal A Chatila; Nima Rezaei; Safa Baris
Journal:  J Clin Immunol       Date:  2022-01-26       Impact factor: 8.542

3.  Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.

Authors:  Kea Martin; Ratiba Touil; Yeter Kolb; Grozdan Cvijetic; Kiichi Murakami; Laura Israel; Fernanda Duraes; David Buffet; Anton Glück; Satoru Niwa; Marc Bigaud; Tobias Junt; Natasa Zamurovic; Philip Smith; Kathy D McCoy; Pamela S Ohashi; Frédéric Bornancin; Thomas Calzascia
Journal:  J Immunol       Date:  2019-10-28       Impact factor: 5.422

4.  Mepazine Inhibits RANK-Induced Osteoclastogenesis Independent of Its MALT1 Inhibitory Function.

Authors:  Laura Meloni; Lynn Verstrepen; Marja Kreike; Jens Staal; Yasmine Driege; Inna S Afonina; Rudi Beyaert
Journal:  Molecules       Date:  2018-11-30       Impact factor: 4.411

5.  Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology.

Authors:  Kea Martin; Ursula Junker; Elaine Tritto; Esther Sutter; Tina Rubic-Schneider; Hannah Morgan; Satoru Niwa; Jianping Li; Achim Schlapbach; Dana Walker; Marc Bigaud; Christian Beerli; Amanda Littlewood-Evans; Bettina Rudolph; Marc Laisney; David Ledieu; Karen Beltz; Jean Quancard; Frédéric Bornancin; Natasa Zamurovic Ribrioux; Thomas Calzascia
Journal:  Front Immunol       Date:  2020-04-30       Impact factor: 7.561

6.  Dietary resistant starch alleviates Escherichia coli-induced bone loss in meat ducks by promoting short-chain fatty acid production and inhibiting Malt1/NF-κB inflammasome activation.

Authors:  Huaiyong Zhang; Simeng Qin; Xiangli Zhang; Pengfei Du; Yao Zhu; Yanqun Huang; Joris Michiels; Quifeng Zeng; Wen Chen
Journal:  J Anim Sci Biotechnol       Date:  2022-08-05

Review 7.  Lessons learned from the study of human inborn errors of innate immunity.

Authors:  Giorgia Bucciol; Leen Moens; Barbara Bosch; Xavier Bossuyt; Jean-Laurent Casanova; Anne Puel; Isabelle Meyts
Journal:  J Allergy Clin Immunol       Date:  2018-08-01       Impact factor: 10.793

Review 8.  The CBM-opathies-A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex.

Authors:  Henry Y Lu; Bradly M Bauman; Swadhinya Arjunaraja; Batsukh Dorjbal; Joshua D Milner; Andrew L Snow; Stuart E Turvey
Journal:  Front Immunol       Date:  2018-09-19       Impact factor: 7.561
  8 in total

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