| Literature DB >> 27108186 |
J M de la Rosa-Trevín1, A Quintana2, L Del Cano3, A Zaldívar3, I Foche4, J Gutiérrez3, J Gómez-Blanco3, J Burguet-Castell3, J Cuenca-Alba3, V Abrishami3, J Vargas3, J Otón3, G Sharov5, J L Vilas3, J Navas3, P Conesa3, M Kazemi3, R Marabini6, C O S Sorzano7, J M Carazo3.
Abstract
In the past few years, 3D electron microscopy (3DEM) has undergone a revolution in instrumentation and methodology. One of the central players in this wide-reaching change is the continuous development of image processing software. Here we present Scipion, a software framework for integrating several 3DEM software packages through a workflow-based approach. Scipion allows the execution of reusable, standardized, traceable and reproducible image-processing protocols. These protocols incorporate tools from different programs while providing full interoperability among them. Scipion is an open-source project that can be downloaded from http://scipion.cnb.csic.es.Keywords: Electron microscopy; Image processing; Reproducibility; Single particle analysis; Software package; Workflows
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Year: 2016 PMID： 27108186 DOI： 10.1016/j.jsb.2016.04.010
Source DB: PubMed Journal: J Struct Biol ISSN： 1047-8477 Impact factor: 2.867