Yuki Abe1, Yoko Shibata2, Akira Igarashi3, Sumito Inoue4, Kento Sato5, Masamichi Sato6, Takako Nemoto7, Maki Kobayashi8, Michiko Nishiwaki9, Tomomi Kimura10, Yoshikane Tokairin11, Takamasa Kayama12, Isao Kubota13. 1. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: yu-abe@med.id.yamagata-u.ac.jp. 2. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: shibata@med.id.yamagata-u.ac.jp. 3. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: akigaras@med.id.yamagata-u.ac.jp. 4. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: sinoue@med.id.yamagata-u.ac.jp. 5. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: k-sato@med.id.yamagata-u.ac.jp. 6. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: m-satoh@med.id.yamagata-u.ac.jp. 7. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: n.takako@med.id.yamagata-u.ac.jp. 8. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: m-kobayashi@med.id.yamagata-u.ac.jp. 9. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: m-nishi@med.id.yamagata-u.ac.jp. 10. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: tomomi-i@med.id.yamagata-u.ac.jp. 11. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: ytokair@med.id.yamagata-u.ac.jp. 12. Global Center of Excellence Program Study Group, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: pulmoyamagata@outlook.jp. 13. Department of Cardiology, Pulmonology, and Nephrology, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address: ikubota@med.id.yamagata-u.ac.jp.
Abstract
BACKGROUND: The forced oscillation technique (FOT) can measure respiratory system resistance and reactance under tidal volume respiration. MostGraph is a device that incorporates the FOT and enables the immediate, three-dimensional visualization of resistance and reactance parameters. The aim of this study was to establish MostGraph reference values for middle-aged and elderly Japanese individuals. METHODS: From 2004 to 2006, 3253 subjects living in Takahata, Yamagata underwent spirometry. Of these, 872 again underwent spirometry in 2011, and 784 (368 men, ages 46-89 years; 416 women, ages 47-90 years) underwent FOT examinations using MostGraph-01. RESULTS: In this study population, 19.0% of the men and 91.5% of the women were life-long never smokers. Abnormal spirometric findings were observed in 30.2% of the men and 14.6% of the women. Although the respiratory system resistance and reactance parameters obtained using MostGraph were not distributed normally, normal distribution was achieved via natural logarithm (R5, R20, Fres, and ALX), square root (R5-R20), or exponential (X5) transformation. Furthermore, the transformed values were converted back to the actual values after determining the values representing one and two standard deviations from the mean. CONCLUSION: Respiratory system resistance and reactance reference values were determined using MostGraph in middle-aged and elderly Japanese individuals who participated in annual health checkups.
BACKGROUND: The forced oscillation technique (FOT) can measure respiratory system resistance and reactance under tidal volume respiration. MostGraph is a device that incorporates the FOT and enables the immediate, three-dimensional visualization of resistance and reactance parameters. The aim of this study was to establish MostGraph reference values for middle-aged and elderly Japanese individuals. METHODS: From 2004 to 2006, 3253 subjects living in Takahata, Yamagata underwent spirometry. Of these, 872 again underwent spirometry in 2011, and 784 (368 men, ages 46-89 years; 416 women, ages 47-90 years) underwent FOT examinations using MostGraph-01. RESULTS: In this study population, 19.0% of the men and 91.5% of the women were life-long never smokers. Abnormal spirometric findings were observed in 30.2% of the men and 14.6% of the women. Although the respiratory system resistance and reactance parameters obtained using MostGraph were not distributed normally, normal distribution was achieved via natural logarithm (R5, R20, Fres, and ALX), square root (R5-R20), or exponential (X5) transformation. Furthermore, the transformed values were converted back to the actual values after determining the values representing one and two standard deviations from the mean. CONCLUSION: Respiratory system resistance and reactance reference values were determined using MostGraph in middle-aged and elderly Japanese individuals who participated in annual health checkups.