Ivan Dedov1, Marina Shestakova2, Massimo Massi Benedetti3, Dominique Simon4, Iakov Pakhomov5, Gagik Galstyan6. 1. Endocrinology Research Centre, Moscow, Russia. 2. Endocrinology Research Centre, Moscow, Russia; I.M. Sechenov First Moscow State Medical University, Moscow, Russia. 3. Hub for International Health Research (HIRS), Perugia, Italy. 4. Diabetes Department and Institute of Cardiometabolism and Metabolism (ICAN), Pitié-Salpétrière Hospital, Paris, France. 5. Sanofi-Aventis Russia, Moscow, Russia. 6. Endocrinology Research Centre, Moscow, Russia; I.M. Sechenov First Moscow State Medical University, Moscow, Russia. Electronic address: galstyangagik964@gmail.com.
Abstract
AIM: To estimate type 2 diabetes mellitus (T2DM) prevalence in Russian adults. METHODS: NATION is a national, epidemiological, cross-sectional study, conducted in Russia. In adults (aged 20-79 years), recruitment was stratified by age, sex, geographic region and settlement type to obtain a representative sample. Recruitment was in public areas with high numbers of people. T2DM was diagnosed by glycated haemoglobin A1c (HbA1c) levels (diabetes: HbA1c ≥6.5% [≥48mmol/mol]; pre-diabetes: HbA1c ≥5.7 to <6.5% [≥39 to <48mmol/mol]). Socio-demographic and anthropometric data were collected. RESULTS: Blood samples from 26,620 subjects were available. Overall, 5.4% were diagnosed with T2DM (previously diagnosed: 2.5%; previously undiagnosed: 2.9%); 19.3% were pre-diabetic. T2DM prevalence increased with age (up to 70 years) and was higher among females than males (6.1% vs. 4.7%, p<0.001). The estimated proportion of subjects with pre-diabetes and T2DM tended to increase with increasing body mass index. T2DM prevalence was higher in rural versus urban populations (6.7% vs. 5.0%, p<0.001). CONCLUSION: In the Russian adult population, 19.3% had pre-diabetes, T2DM prevalence was 5.4%, and 54% of subjects with diabetes were previously undiagnosed. These results may help to develop a new T2DM predictive, preventative and management programme in Russia.
AIM: To estimate type 2 diabetes mellitus (T2DM) prevalence in Russian adults. METHODS: NATION is a national, epidemiological, cross-sectional study, conducted in Russia. In adults (aged 20-79 years), recruitment was stratified by age, sex, geographic region and settlement type to obtain a representative sample. Recruitment was in public areas with high numbers of people. T2DM was diagnosed by glycated haemoglobin A1c (HbA1c) levels (diabetes: HbA1c ≥6.5% [≥48mmol/mol]; pre-diabetes: HbA1c ≥5.7 to <6.5% [≥39 to <48mmol/mol]). Socio-demographic and anthropometric data were collected. RESULTS: Blood samples from 26,620 subjects were available. Overall, 5.4% were diagnosed with T2DM (previously diagnosed: 2.5%; previously undiagnosed: 2.9%); 19.3% were pre-diabetic. T2DM prevalence increased with age (up to 70 years) and was higher among females than males (6.1% vs. 4.7%, p<0.001). The estimated proportion of subjects with pre-diabetes and T2DM tended to increase with increasing body mass index. T2DM prevalence was higher in rural versus urban populations (6.7% vs. 5.0%, p<0.001). CONCLUSION: In the Russian adult population, 19.3% had pre-diabetes, T2DM prevalence was 5.4%, and 54% of subjects with diabetes were previously undiagnosed. These results may help to develop a new T2DM predictive, preventative and management programme in Russia.
Authors: Gagik R Galstyan; Farida V Valeeva; Svetlana I Motkova; Elena V Surkova; Larisa V Savelyeva; Larisa M Rudina; Krishnan Ramanathan; Ekaterina Sokareva; Kristina Bondareva; Marina V Shestakova Journal: Obes Sci Pract Date: 2021-04-09
Authors: Mukharram M Bikbov; Rinat R Fayzrakhmanov; Gyulli M Kazakbaeva; Rinat M Zainullin; Inga I Arslangareeva; Timur R Gilmanshin; Venera F Salavatova; Nikolai A Nikitin; Svetlana R Mukhamadieva; Dilya F Yakupova; Renat I Khikmatullin; Artur F Zaynetdinov; Yulia V Uzianbaeva; Said K Aminev; Ildar F Nuriev; Jost B Jonas Journal: PLoS One Date: 2019-04-22 Impact factor: 3.240
Authors: Olena Iakunchykova; Maria Averina; Tom Wilsgaard; Sofia Malyutina; Alexander V Kudryavtsev; Sarah Cook; Sarah Wild; Anne Elise Eggen; Laila Arnesdatter Hopstock; David A Leon Journal: BMJ Open Diabetes Res Care Date: 2021-03
Authors: Gadadharan Vijayakumar; Sreeja Manghat; Revathi Vijayakumar; Leena Simon; Liss Maria Scaria; Aswathi Vijayakumar; Ganapathy K Sreehari; V Raman Kutty; Arun Rachana; Abdul Jaleel Journal: BMC Public Health Date: 2019-01-31 Impact factor: 3.295