Literature DB >> 27106275

Diverticulitis: does age matter?

Nir Horesh1, Chaya Shwaartz1, Imri Amiel1, Avinoam Nevler1, Esther Shabtai1, Alexander Lebedeyev1, Roi Nadler1, Danny Rosin1, Mordechai Gutman1, Oded Zmora1.   

Abstract

OBJECTIVE: Acute diverticulitis has been traditionally associated with worse outcome in young patients, indicating a more aggressive surgical approach is required for them. The aim of this study was to assess whether acute diverticulitis was more virulent in young patients.
METHODS: A retrospective, cross-sectional study included all patients who were admitted for a first episode of acute diverticulitis between January 2004 and December 2013. The patients were divided into two groups (≤50 years and >50 years) based on their age. Patients' characteristics, clinical and surgical data were recorded and analyzed.
RESULTS: Overall, 636 patients were included in the database, including 177 (27.8%) in the younger group and 459 in the elder group. There were no significant differences between the groups in disease complexity, peritonitis, laboratory work-up, vital signs on presentation, bowel obstruction or the presence of fistula and abscess in need of drainage. Younger patients had more free extra-luminal air on computed tomography (CT) scan (P = 0.03). Surgical data, including the intra-operative modified Hinchey score and the need for emergency and additional surgery did not significantly differ between the two groups. Young patients had more readmissions (P = 0.01) due to acute diverticulitis, diverticular complications and elective surgery. Length of hospital stay (P = 0.0001) was longer and postoperative complications were more common in the elder patients.
CONCLUSIONS: The clinical presentation of acute diverticulitis does not seem to be worse in the young population. Younger patients tend to have a more severe presentation on CT scan and more readmissions, but this did not translate to a more severe disease course.
© 2016 Chinese Medical Association Shanghai Branch, Chinese Society of Gastroenterology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  age groups; colorectal surgery; complications; diverticulitis; epidemiology

Mesh:

Year:  2016        PMID: 27106275     DOI: 10.1111/1751-2980.12350

Source DB:  PubMed          Journal:  J Dig Dis        ISSN: 1751-2972            Impact factor:   2.325


  6 in total

Review 1.  Acute Diverticulitis in Young Patients: A Review of the Changing Epidemiology and Etiology.

Authors:  Greg A Turner; Michael J O'Grady; Rachel V Purcell; Frank A Frizelle
Journal:  Dig Dis Sci       Date:  2021-03-31       Impact factor: 3.199

2.  Factors Associated with Repeated Health Resource Utilization in Patients with Diverticulitis.

Authors:  Steven N Mathews; Ryan Lamm; Jie Yang; Lijuan Kang; Dana Telem; Aurora D Pryor; Mark Talamini; Jill Genua
Journal:  J Gastrointest Surg       Date:  2016-09-09       Impact factor: 3.452

Review 3.  Pathophysiology and Epidemiology of Diverticular Disease.

Authors:  Stephanie D Talutis; F Angela H Kuhnen
Journal:  Clin Colon Rectal Surg       Date:  2020-12-08

4.  The Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery.

Authors:  Andrew S Miller; Kathryn Boyce; Benjamin Box; Matthew D Clarke; Sarah E Duff; Niamh M Foley; Richard J Guy; Lisa H Massey; George Ramsay; Dominic A J Slade; James A Stephenson; Phil J Tozer; Danette Wright
Journal:  Colorectal Dis       Date:  2021-02       Impact factor: 3.917

Review 5.  A systematic review and meta-analysis of outpatient treatment for acute diverticulitis.

Authors:  S T van Dijk; K Bos; M G J de Boer; W A Draaisma; W A van Enst; R J F Felt; B R Klarenbeek; J A Otte; J B C M Puylaert; A A W van Geloven; M A Boermeester
Journal:  Int J Colorectal Dis       Date:  2018-03-12       Impact factor: 2.571

6.  Predictors of Clinical Course and Outcomes of Acute Diverticulitis: The Role of Age and Ethnicity.

Authors:  Randa Taher; Yael Kopelman; Abdel-Rauf Zeina; Amir Mari; Fadi Abu Baker
Journal:  Medicina (Kaunas)       Date:  2021-11-19       Impact factor: 2.430

  6 in total

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