Literature DB >> 27105205

Improving Adherence to Adjuvant Endocrine Therapy in Breast Cancer Through a Therapeutic Educational Approach: A Feasibility Study
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Aurélie Bourmaud1, Vanessa Rousset1, Véronique Regnier-Denois1, Olivier Collard1, Jean-Philippe Jacquin1, Yacine Merrouche1, Joelle Lapoirie1, Fabien Tinquaut1, Laurence Lataillade2, Franck Chauvin1.   

Abstract

PURPOSE/
OBJECTIVES: To develop and test the feasibility of a tailored therapeutic educational program, with the aim of improving adherence to oral endocrine adjuvant chemotherapy in women with breast cancer. 
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DESIGN: A qualitative study to identify educational needs and a feasibility study assessing the efficacy of the program.
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SETTING: A comprehensive cancer center, the Lucien Neuwirth Cancer Institute in Saint-Priest-en-Jarez, France.
. SAMPLE: Two consecutive samples (N = 11, N = 6) of women taking adjuvant oral endocrine chemotherapy for breast cancer. 
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METHODS: A mixed qualitative and quantitative method was used. The participants' representations of disease and treatment were explored through one-on-one interviews and then translated into educational needs, which were used to develop a tailored therapeutic education program. The pilot study evaluated the reach and efficacy using before-and-after comparisons. 
. MAIN RESEARCH VARIABLES: Educational objectives, knowledge, trust in the treatment, and anxiety.
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FINDINGS: Five educational objectives (acquiring knowledge, improving communication skills, managing anxiety, managing side effects, and improving adherence) were identified through 11 interviews. A three-session program was developed. Eight of the 23 patients invited to participate in a pilot study accepted, and six completed the intervention. Knowledge improved from 38.9 of 100 preintervention to 69.4 of 100 postintervention (p = 0.045). Trust in treatment showed a trend to improvement from 5.5 of 10 to 8 of 10 (p = 0.14), but anxiety did not change significantly; anxiety went from 6 to 7 (p = 0.88).
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CONCLUSIONS: Results from the feasibility study showed promising efficacy for the educational objectives and provided information about how the program could be improved. 
. IMPLICATIONS FOR NURSING: Tailored educational programs conducted by trained nurses may help patients to adhere to and live with the effects of endocrine therapy.

Entities:  

Keywords:  adherence; adjuvant endocrine therapy; breast cancer; empowerment; quantitative and qualitative mixed method; side effects; therapeutic educational program

Mesh:

Substances:

Year:  2016        PMID: 27105205     DOI: 10.1188/16.ONF.E94-E103

Source DB:  PubMed          Journal:  Oncol Nurs Forum        ISSN: 0190-535X            Impact factor:   2.172


  3 in total

1.  Endocrine therapy initiation, discontinuation and adherence and breast imaging among 21-gene recurrence score assay-eligible women under age 65.

Authors:  Suzanne C O'Neill; Claudine Isaacs; Filipa Lynce; Deena Mary Atieh Graham; Calvin Chao; Vanessa B Sheppard; Yingjun Zhou; Chunfu Liu; Nandini Selvam; Marc D Schwartz; Arnold L Potosky
Journal:  Breast Cancer Res       Date:  2017-03-31       Impact factor: 6.466

2.  Breast Nurse Intervention to Improve Adherence to Endocrine Therapy Among Breast Cancer Patients in South Ethiopia.

Authors:  Sefonias Getachew; Adamu Addissie; Edom Seife; Tariku Wakuma; Susanne Unverzagt; Ahmedin Jemal; Lesley Taylor; Andreas Wienke; Eva J Kantelhardt
Journal:  Oncologist       Date:  2022-08-05       Impact factor: 5.837

3.  Patient-Reported Outcomes From Phase III Neoadjuvant Systemic Trial Comparing Neoadjuvant Chemotherapy With Neoadjuvant Endocrine Therapy in Pre-Menopausal Patients With Estrogen Receptor-Positive and HER2-Negative, Lymph Node-Positive Breast Cancer.

Authors:  Sungchan Gwark; Sei Hyun Ahn; Woo Chul Noh; Eun Sook Lee; Yongsik Jung; Lee Su Kim; Wonshik Han; Seok Jin Nam; Gyungyub Gong; Seon-Ok Kim; Hee Jeong Kim
Journal:  Front Oncol       Date:  2021-07-02       Impact factor: 6.244

  3 in total

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