Literature DB >> 27105111

Non-canonical RAN Translation of CGG Repeats Has Canonical Requirements.

Diana C Cox1, Thomas A Cooper2.   

Abstract

Repeat expansions cause dominantly inherited neurological disorders. In this issue of Molecular Cell, Kearse et al. (2016) examine the requirements for RAN translation of the CGG repeats that cause fragile X-associated tremor/ataxia syndrome, revealing similarities and differences with canonical translation.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27105111     DOI: 10.1016/j.molcel.2016.04.004

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  1 in total

1.  Lack of RAN-mediated toxicity in Huntington's disease knock-in mice.

Authors:  Su Yang; Huiming Yang; Luoxiu Huang; Luxiao Chen; Zhaohui Qin; Shihua Li; Xiao-Jiang Li
Journal:  Proc Natl Acad Sci U S A       Date:  2020-02-06       Impact factor: 11.205

  1 in total

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