| Literature DB >> 27104311 |
Raheel Samuel1,2, Odgerel Badamjav1, Kristin E Murphy3, Darshan P Patel4, Jiyoung Son5, Bruce K Gale2, Douglas T Carrell1,4, James M Hotaling1,4.
Abstract
Non-obstructive azoospermia (NOA) is a severe form of infertility accounting for 10% of infertile men. Microdissection testicular sperm extraction (microTESE) includes a set of clinical protocols from which viable sperm are collected from patients (suffering from NOA), for intracytoplasmic sperm injection (ICSI). Clinical protocols associated with the processing of a microTESE sample are inefficient and significantly reduce the success of obtaining a viable sperm population. In this review we highlight the sources of these inefficiencies and how these sources can possibly be removed by microfluidic technology and single-cell Raman spectroscopy.Entities:
Keywords: IVF; microTESE; microfluidics; sperm separation
Mesh：
Year: 2016 PMID： 27104311 DOI： 10.3109/19396368.2016.1159748
Source DB: PubMed Journal: Syst Biol Reprod Med ISSN： 1939-6368 Impact factor: 3.061