Literature DB >> 27103972

Interleukin-6 Kinetics can be Useful for Early Treatment Monitoring of Severe Bacterial Sepsis and Septic Shock.

Thomas Klag1, Giulio Cantara2, Udo Sechtem2, Anastasios Athanasiadis2.   

Abstract

Early appropriate anti-microbial therapy is necessary to improve outcomes of septic patients. We describe 20 case histories of patients with severe bacterial sepsis regarding kinetics of several biomarkers. We found that interleukin-6 is able to predict survival and might be able to evaluate appropriateness of anti-microbial therapy.

Entities:  

Keywords:  C reactive protein; Interleukin-6; bacterial sepsis; monitoring; procalcitonin

Year:  2016        PMID： 27103972      PMCID： PMC4815941          DOI： 10.4081/idr.2016.6213

Source DB:  PubMed          Journal:  Infect Dis Rep        ISSN： 2036-7430


  9 in total

Review 1.  Severe sepsis and septic shock.

Authors:  Derek C Angus; Tom van der Poll
Journal:  N Engl J Med       Date:  2013-08-29       Impact factor: 91.245

2.  Do health plans have a role in limiting antibiotic resistance?

Authors:  Joseph Burns
Journal:  Manag Care       Date:  2014-04

3.  Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial.

Authors:  Jens U Jensen; Lars Hein; Bettina Lundgren; Morten H Bestle; Thomas T Mohr; Mads H Andersen; Klaus J Thornberg; Jesper Løken; Morten Steensen; Zoe Fox; Hamid Tousi; Peter Søe-Jensen; Anne Ø Lauritsen; Ditte Strange; Pernille L Petersen; Nanna Reiter; Søren Hestad; Katrin Thormar; Paul Fjeldborg; Kim M Larsen; Niels E Drenck; Christian Ostergaard; Jesper Kjær; Jesper Grarup; Jens D Lundgren
Journal:  Crit Care Med       Date:  2011-09       Impact factor: 7.598

4.  Characteristics of surgical patients receiving inappropriate empiric antimicrobial therapy.

Authors:  Stephen W Davies; Jimmy T Efird; Christopher A Guidry; Tjasa Hranjec; Rosemarie Metzger; Brian R Swenson; Robert G Sawyer
Journal:  J Trauma Acute Care Surg       Date:  2014-10       Impact factor: 3.313

5.  Procalcitonin as a diagnostic marker and IL-6 as a prognostic marker for sepsis.

Authors:  Dong Wook Jekarl; So-Young Lee; Jehoon Lee; Yeon-Joon Park; Yonggoo Kim; Jeong Ho Park; Jung Hee Wee; Seung Pill Choi
Journal:  Diagn Microbiol Infect Dis       Date:  2013-02-04       Impact factor: 2.803

6.  Bacteraemia incidence, causative organisms and resistance patterns, antibiotic strategies and outcomes in a single university hospital ICU: continuing improvement between 2000 and 2013.

Authors:  Vincenzo De Santis; Mihaela Gresoiu; Alberto Corona; A Peter R Wilson; Mervyn Singer
Journal:  J Antimicrob Chemother       Date:  2014-09-03       Impact factor: 5.790

Review 7.  The efficacy of procalcitonin as a biomarker in the management of sepsis: slaying dragons or tilting at windmills?

Authors:  Prasanna Sridharan; Ronald S Chamberlain
Journal:  Surg Infect (Larchmt)       Date:  2013-11-25       Impact factor: 2.150

Review 8.  Biomarkers of sepsis.

Authors:  James D Faix
Journal:  Crit Rev Clin Lab Sci       Date:  2013 Jan-Feb       Impact factor: 6.250

9.  Implementation of a computerized decision support system to improve the appropriateness of antibiotic therapy using local microbiologic data.

Authors:  Manuel Rodriguez-Maresca; Antonio Sorlozano; Magnolia Grau; Rocio Rodriguez-Castaño; Andres Ruiz-Valverde; Jose Gutierrez-Fernandez
Journal:  Biomed Res Int       Date:  2014-08-17       Impact factor: 3.411
  9 in total
  2 in total

1.  Reduction in the IL-6 level at 24 h after admission to the intensive care unit is a survival predictor for Vietnamese patients with sepsis and septic shock: a prospective study.

Authors:  Pham Thi Ngoc Thao; Ton Thanh Tra; Nguyen Truong Son; Koji Wada
Journal:  BMC Emerg Med       Date:  2018-11-06

Review 2.  The Importance of Haemogram Parameters in the Diagnosis and Prognosis of Septic Patients.

Authors:  Alina Elena Orfanu; Cristina Popescu; Anca Leuștean; Anca Ruxandra Negru; Cătălin Tilişcan; Victoria Aramă; Ștefan Sorin Aramă
Journal:  J Crit Care Med (Targu Mures)       Date:  2017-08-19
  2 in total

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