Literature DB >> 27103171

Neurodegeneration: HIF-PHD inhibition ameliorates damage after brain haemorrhage.

Sarah Crunkhorn.   

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Year:  2016        PMID: 27103171     DOI: 10.1038/nrd.2016.72

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN: 1474-1776            Impact factor:   84.694


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  1 in total

1.  Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.

Authors:  Saravanan S Karuppagounder; Ishraq Alim; Soah J Khim; Megan W Bourassa; Sama F Sleiman; Roseleen John; Cyrille C Thinnes; Tzu-Lan Yeh; Marina Demetriades; Sandra Neitemeier; Dana Cruz; Irina Gazaryan; David W Killilea; Lewis Morgenstern; Guohua Xi; Richard F Keep; Timothy Schallert; Ryan V Tappero; Jian Zhong; Sunghee Cho; Frederick R Maxfield; Theodore R Holman; Carsten Culmsee; Guo-Hua Fong; Yijing Su; Guo-li Ming; Hongjun Song; John W Cave; Christopher J Schofield; Frederick Colbourne; Giovanni Coppola; Rajiv R Ratan
Journal:  Sci Transl Med       Date:  2016-03-02       Impact factor: 17.956

  1 in total

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