M C Nolff1, S Reese2, M Fehr3, R Dening3, A Meyer-Lindenberg1. 1. Clinic for Small Animal Surgery and Reproduction, Ludwig-Maximilians-University, Veterinärstrasse 13, Munich, 80539, Germany. 2. Department for Basic Veterinary Sciences, Ludwig-Maximilians-University, Professor-Huber-Platz 2, Munich, 80539, Germany. 3. Small Animal Clinic, University of Veterinary Medicine of Hannover, Bünteweg 2, 30559, Hannover, Germany.
Abstract
OBJECTIVE: To describe the bacterial bio-burden of open-treated wounds and make comparisons with bite wounds. DESIGN: Retrospective multicentre study. SAMPLE: Microbial culture between 2011 and 2013 from open-treated wounds in dogs and cats (initiation of therapy n=88, follow-up n=52) were compared to those from bite wounds (n=184). PROCEDURES: Bacteria were identified and tested for antibiotic susceptibility by two accredited laboratories. RESULTS: In total, 77/88 (88%) of open-treated wounds yielded positive bacterial cultures at the beginning of treatment, decreasing to 27/52 (52%) during treatment. Upon initial evaluation, 42/88 (48 %) of open-treated wounds were considered infected with multi-drug-resistant bacteria, with a drop to 22/52 (41%) during therapy. Bite wounds yielded fewer positive cultures 88/184 (48%) with only 11/182 (6%) being affected by multi-drug-resistant bacteria. Bacteria found most commonly in open-treated wounds were Enterococcus subspecies, Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa. CONCLUSION: The bacterial populations of open-treated wounds differed markedly from the bite wounds. The high incidence of multi-drug-resistant strains in open wounds highlights the need for alternatives to antibiotics.
OBJECTIVE: To describe the bacterial bio-burden of open-treated wounds and make comparisons with bite wounds. DESIGN: Retrospective multicentre study. SAMPLE: Microbial culture between 2011 and 2013 from open-treated wounds in dogs and cats (initiation of therapy n=88, follow-up n=52) were compared to those from bite wounds (n=184). PROCEDURES: Bacteria were identified and tested for antibiotic susceptibility by two accredited laboratories. RESULTS: In total, 77/88 (88%) of open-treated wounds yielded positive bacterial cultures at the beginning of treatment, decreasing to 27/52 (52%) during treatment. Upon initial evaluation, 42/88 (48 %) of open-treated wounds were considered infected with multi-drug-resistant bacteria, with a drop to 22/52 (41%) during therapy. Bite wounds yielded fewer positive cultures 88/184 (48%) with only 11/182 (6%) being affected by multi-drug-resistant bacteria. Bacteria found most commonly in open-treated wounds were Enterococcus subspecies, Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa. CONCLUSION: The bacterial populations of open-treated wounds differed markedly from the bite wounds. The high incidence of multi-drug-resistant strains in open wounds highlights the need for alternatives to antibiotics.
Authors: Andrey Ethan Rubin; Osman Berk Usta; Rene Schloss; Martin Yarmush; Alexander Golberg Journal: Adv Wound Care (New Rochelle) Date: 2019-04-03 Impact factor: 4.730
Authors: Søren Saxmose Nielsen; Dominique Joseph Bicout; Paolo Calistri; Elisabetta Canali; Julian Ashley Drewe; Bruno Garin-Bastuji; José Luis Gonzales Rojas; Christian Gortázar; Mette Herskin; Virginie Michel; Miguel Ángel Miranda Chueca; Barbara Padalino; Paolo Pasquali; Helen Clare Roberts; Hans Spoolder; Karl Ståhl; Antonio Velarde; Arvo Viltrop; Christoph Winckler; Francesca Baldinelli; Alessandro Broglia; Lisa Kohnle; Julio Alvarez Journal: EFSA J Date: 2022-05-03