UK Renal Registry 18th Annual Report: Chapter 1 UK Renal Replacement Therapy Incidence in 2014: National and Centre-specific Analyses.

The incidence rate in the UK increased from 109 per million population (pmp) in 2013 to 115 pmp in 2014 reflecting renal replacement therapy (RRT) initiation for 7,411 new patients. The increase in incidence rate from 2013 to 2014 was seen in England and Scotland (although rates in Scotland have fluctuated around this level since 2008) but not Wales and Northern Ireland. The median age of all incident patients was 64.8 years but this was highly dependant on ethnicity (66.4 for White incident patients; 58.7 for non- White patients). Diabetic renal disease remained the single most common cause of renal failure (26.9%). By 90 days, 66.3% of patients were on haemodialysis, 19.1% on peritoneal dialysis, 9.7% had a functioning transplant and 4.8% had died or stopped treatment. By contrast, in 2007, at 90 days 67% were on HD, 21% PD and only 5% were transplanted. The percentage of patients still on RRT at 90 days who had a functioning transplant at 90 days varied between centres from 0% to 33% (between 7% and 33% for transplanting centres and between 0% and 21% for non-transplanting centres). The mean eGFR at the start of RRT was 8.6 ml/min/1.73 m2 similar to the previous four years. Late presentation (,90 days) fell from 23.9% in 2006 to 17.8% in 2014.