Literature DB >> 27098896

Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer.

Yueling Yuan1, Tiange Cai2, Xi Xia1, Ronghua Zhang1, Peter Chiba3, Yu Cai1,4.   

Abstract

Breast cancer is a serious threat to women's health, because multidrug resistance (MDR) has hampered treatment and prognosis. Nanodelivery of anticancer agents is a new technology to be exploited in the treatment of patients, because it bypasses multispecific drug efflux transporters such as P-glycoprotein (ABCB1), multidrug resistance protein-1 (MRP1, ABCC1) and breast cancer resistance protein (BCRP, ABCG2). Drugs can be delivered to tumor tissue by passive and active tumor targeting strategies, which may reduce or reverse drug resistance. This review will mainly focus on MDR-associated proteins, as well as various nanoparticle formulations developed to overcome MDR in breast cancer.

Entities:  

Keywords:  Breast cancer; mechanisms; multidrug resistance; nanoparticles

Mesh：

Substances：

Year:  2016        PMID： 27098896     DOI： 10.1080/10717544.2016.1178825

Source DB:  PubMed          Journal:  Drug Deliv        ISSN： 1071-7544            Impact factor:   6.419


  32 in total

1.  Microfluidic device for the analysis of MDR cancerous cell-derived exosomes' response to nanotherapy.

Authors:  Ruogu Qi; Guixian Zhu; Yu Wang; Suhong Wu; Shengliang Li; Dechen Zhang; Yang Bu; Gauri Bhave; Ruixuan Han; Xuewu Liu
Journal:  Biomed Microdevices       Date:  2019-03-25       Impact factor: 2.838

2.  Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer.

Authors:  Noha M Badawi; Yasmeen M Attia; Dina M El-Kersh; Olfat A Hammam; Maha K A Khalifa
Journal:  Int J Nanomedicine       Date:  2022-02-18

Review 3.  Multifunctional nanomedicines for targeting epidermal growth factor receptor in colorectal cancer.

Authors:  Mostafa Akbarzadeh Khiavi; Azam Safary; Jaleh Barar; Amir Ajoolabady; Mohammad Hossein Somi; Yadollah Omidi
Journal:  Cell Mol Life Sci       Date:  2019-09-28       Impact factor: 9.261

4.  Comprehensive Evaluation of the Toxicity and Biosafety of Plasma Polymerized Nanoparticles.

Authors:  Praveesuda L Michael; Yuen Ting Lam; Juichien Hung; Richard P Tan; Miguel Santos; Steven G Wise
Journal:  Nanomaterials (Basel)       Date:  2021-04-29       Impact factor: 5.076

Review 5.  Nanoparticles as Theranostic Vehicles in Experimental and Clinical Applications-Focus on Prostate and Breast Cancer.

Authors:  Jörgen Elgqvist
Journal:  Int J Mol Sci       Date:  2017-05-20       Impact factor: 5.923

Review 6.  Anticancer Activities of Surfactin and Potential Application of Nanotechnology Assisted Surfactin Delivery.

Authors:  Yuan-Seng Wu; Siew-Ching Ngai; Bey-Hing Goh; Kok-Gan Chan; Learn-Han Lee; Lay-Hong Chuah
Journal:  Front Pharmacol       Date:  2017-10-26       Impact factor: 5.810

7.  Indomethacin-based stimuli-responsive micelles combined with paclitaxel to overcome multidrug resistance.

Authors:  Shuanghu Wang; Xueying Tan; Shujuan Li; Yunfang Zhou; Peiwu Geng; Ailian Hua; Aiping Deng; Zhihong Yu
Journal:  Oncotarget       Date:  2017-11-30

8.  Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer.

Authors:  Ravi Doddapaneni; Ketan Patel; Nusrat Chowdhury; Mandip Singh
Journal:  Sci Rep       Date:  2017-11-20       Impact factor: 4.379

Review 9.  Cancer resistance to treatment and antiresistance tools offered by multimodal multifunctional nanoparticles.

Authors:  Eudald Casals; Muriel F Gusta; Macarena Cobaleda-Siles; Ana Garcia-Sanz; Victor F Puntes
Journal:  Cancer Nanotechnol       Date:  2017-10-26

Review 10.  Drug delivery approaches for breast cancer.

Authors:  Santosh Kumar Singh; Shriti Singh; James W Lillard; Rajesh Singh
Journal:  Int J Nanomedicine       Date:  2017-08-24
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